NCT02276079 is a NA clinical trial of Aerobic Exercise in Brain Concussion, sponsored by University of Florida.

Who is sponsoring NCT02276079?

NCT02276079 is sponsored by University of Florida.

What drugs are being tested in NCT02276079?

Interventions in NCT02276079: Aerobic Exercise, Non-Aerobic Exercise.

What condition does NCT02276079 study?

NCT02276079 studies Brain Concussion.

Is NCT02276079 still recruiting?

NCT02276079 is currently completed. Last updated 4 December 2018.

Last reviewed 2018-12-04 · How we verify

NCT02276079

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury

Completed NA Last updated 4 December 2018

What this trial tests

NA trial testing Aerobic Exercise in Brain Concussion in 39 participants. Completed in 22 December 2016.

Timeline

17 February 2015

Primary endpoint
22 December 2016

22 December 2016

Quick facts

Lead sponsor	University of Florida
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	39
Start date	17 February 2015
Primary completion	22 December 2016
Estimated completion	22 December 2016
Sites	1 location across United States

Drugs / interventions tested

Aerobic Exercise — full drug profile →
Non-Aerobic Exercise

Conditions studied

Brain Concussion — all drugs for Brain Concussion →

Sponsor

University of Florida

Who can join

Adults 18 to 40, any sex, with Brain Concussion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study is a "proof-of-principle" project to examine the safety and feasibility of implementing a 1-week aerobic exercise program in the post-acute phase after mild traumatic brain injury (mTBI). The study will define the extent to which the exercise program improves recovery from mTBI in terms of relevant functional outcomes (cognition, mood, and physical status) and biomarkers (peripheral brain-derived neurotrophic factor \[BDNF\] concentration).

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Status of precision medicine approaches to traumatic brain injury.
Reddi S, Thakker-Varia S, Alder J, Giarratana AO. · · 2022 · cited 30× · PMID 35259824 · DOI 10.4103/1673-5374.335824
Fitness training for cardiorespiratory conditioning after traumatic brain injury.
Hassett L, Moseley AM, Harmer AR. · · 2017 · cited 20× · PMID 29286534 · DOI 10.1002/14651858.cd006123.pub3
The Effect of Aerobic Exercise on Concussion Recovery: A Pilot Clinical Trial.
Snyder AR, Greif SM, Clugston JR, FitzGerald DB, et al · · 2021 · cited 12× · PMID 34548116 · DOI 10.1017/s1355617721000886
Neurotrophic factors: promising candidates in tissue regeneration.
Xiao N. · · 2016 · cited 7× · PMID 27335553 · DOI 10.4103/1673-5374.182696

Verify or expand the search:

Other trials of Aerobic Exercise

Trials testing the same drug.

NCT07517224 — Assessing the Effect of an Aerobic Exercise Program on Vascular Function in Women With Non-Metastatic Breast Cancer · NA · not yet recruiting
NCT07444333 — Cardiac Output and Fatigue in Friedreich's Ataxia · NA · not yet recruiting
NCT07182006 — Exercise as Medicine for Pediatric Chronic Pain · NA · not yet recruiting
NCT07404319 — Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment Resistant · NA · not yet recruiting
NCT07302204 — Efficacy of Aerobic Exercise Versus Therapeutic Exercises on Exercise-induced Hypoalgesia in Knee Osteoarthritis · NA · recruiting

Other recruiting trials for Brain Concussion

Currently open trials in the same condition.

NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
NCT06616272 — Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain · NA · recruiting
NCT05498038 — Exercise Reset for Concussion in a Military Environment · NA · recruiting
NCT06413173 — Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric) · NA · recruiting
NCT06365944 — Concussion in French Non-professional Handball League : Efficiency of a Concussion Protocol, the White Card Process · recruiting

Other University of Florida trials

Trials by the same sponsor.

NCT03429413 — Maximizing HPV Vaccination: Real-time Reminders, Guidance, and Recommendations - Part 4: Feasibility Trial · NA · not yet recruiting
NCT06127550 — taVNS for Letter Learning in Dyslexia · NA · suspended
NCT07507214 — Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athl · Phase 2, PHASE3 · not yet recruiting
NCT07492316 — RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) · Phase 1 · not yet recruiting
NCT06670794 — Using Ecological Momentary Data to Inform a Web Intervention for Romantic Partners Concerned About Their Loved Ones' Dri · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02276079 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Florida
Last refreshed: 4 December 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02276079.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing