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NCT02066337
Effect of Ozone Gel on Alveolar Bone Density and Superoxide Dismutase in Chronic Periodontitis: A Randomized Controlled Clinical Study
Phase 2 trial testing scaling and root planing in Periodontal Diseases in 40 participants. Completed in 1 February 2014.
1 January 2014
Quick facts
| Lead sponsor | October 6 University |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 March 2013 |
| Primary completion | 1 January 2014 |
| Estimated completion | 1 February 2014 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- scaling and root planing
- placebo gel
- Ozonated olive oil gel — full drug profile →
Conditions studied
- Periodontal Diseases — all drugs for Periodontal Diseases →
Sponsor
October 6 University
Who can join
Adults 30 to 60, any sex, with Periodontal Diseases. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Superoxide dismutase activity
Time frame: 6 months
Superoxide dismutase activity in the gingival crevicular fluid was carried out at baseline, 1, 3 and 6 months post treatment.
Sponsor's own description
To evaluate the efficacy of locally delivered ozone gel as an adjunct to conventional periodontal therapy on selected clinical parameters as well as alveolar bone density (BD) and superoxide dismutase (SOD) activity in patient with chronic periodontitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT02066337
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of scaling and root planing
Trials testing the same drug.
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- NCT05546788 — Hydroxylated Polymethoxy Flavones Solid Dispersion in Treatment of Periodontitis · Phase 1 · unknown
- NCT05995431 — Impact of Bruxism in the Outcome of Subgingival Instrumentation for the Management of Stage 2 and Stage 3 Periodontitis. · NA · recruiting
- NCT04392804 — Efficacy of Intraseptal Anesthesia of 4% Articaine With Epinephrine Achieved by Computer-controlled Delivery System · unknown
Other recruiting trials for Periodontal Diseases
Currently open trials in the same condition.
- NCT07358104 — Efficacy of Camel Whey Protein and Camel Whey Protein Nanoparticles for Treating Intra-bony Periodontal Defects · NA · active not recruiting
- NCT07312045 — HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical T · recruiting
- NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
- NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
- NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting
Other October 6 University trials
Trials by the same sponsor.
- NCT07235072 — Passive Fit and Time Efficiency in All On-X Implants Protocols Using Photogrammetry, Splinted Scan Bodies, and Conventio · NA · not yet recruiting
- NCT07403851 — Effect of Scanning Technology on the Accuracy of Digitally Customized Intraradicular Attachments · NA · not yet recruiting
- NCT07305792 — High Tone Power Therapy on Lumbosacral Radiculopathy Patients · NA · completed
- NCT07132736 — Impact of Underwater Exercise Versus Regular Aerobic Exercise on Quality of Life and Power of Muscle · NA · recruiting
- NCT07350655 — Efficacy of Virtual Reality-based Training in Patients With Chronic Non-specific Low Back Pain · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02066337 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by October 6 University
- Last refreshed: 19 February 2014
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02066337.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing