NCT01294696: SORT

Survey of Osteoarthritis Real World Therapies (SORT)

Completed Results posted Last updated 12 August 2024

What this trial tests

trial testing Standard of care for treatment of osteoarthritis (OA) of knee(s) in Osteoarthritis in 1,261 participants. Completed in 1 January 2013.

Timeline

1 October 2010

Primary endpoint
1 January 2013

1 January 2013

Quick facts

Lead sponsor	Organon and Co
Status	Completed
Study type	OBSERVATIONAL
Enrollment	1,261
Start date	1 October 2010
Primary completion	1 January 2013
Estimated completion	1 January 2013

Drugs / interventions tested

• Standard of care for treatment of osteoarthritis (OA) of knee(s) — full drug profile →

Conditions studied

• Osteoarthritis — all drugs for Osteoarthritis →

Sponsor

Organon and Co — full company profile →

Who can join

50 and older, any sex, with Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

• Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline
  Time frame: Baseline (Day 1)
  Participant pain at baseline was recorded using the Brief Pain Inventory (BPI). The BPI is an inventory of subject-reported questions, where for each pain severity item the response scale is 0 = No Pain and 10 = Worst Pain You Can Imagine. The questions refer to pain due to osteoarthritis in the affected knee in the last week: at its worst, at its least, on the average, and right now. Adequate pai
• Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Month 12
  Time frame: Month 12
  Participant pain at baseline was recorded using the Brief Pain Inventory (BPI). The BPI is an inventory of subject-reported questions, where for each pain severity item the response scale is 0 = No Pain and 10 = Worst Pain You Can Imagine. The questions refer to pain in the last week: at its worst, at its least, on the average, and right now. Adequate pain control was defined as a score of \<=4 on

Sponsor's own description

This was a study to estimate the proportion of participants with osteoarthritis of the knee(s) who were treated with oral or topical analgesics for their symptoms, who did and did not report adequate pain relief at Baseline and to characterize their pain level over a 12-month follow-up period.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Inadequate pain relief and large functional loss among patients with knee osteoarthritis: evidence from a prospective multinational longitudinal study of osteoarthritis real-world therapies.
   Conaghan PG, Peloso PM, Everett SV, Rajagopalan S, et al · · 2015 · cited 94× · PMID 25150513 · DOI 10.1093/rheumatology/keu332