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NCT00832884
IV Lacosamide: The Safety of Intravenous Lacosamide
Phase 4 trial testing Lacosamide in Epilepsy in 40 participants. Completed in 1 November 2012.
1 May 2012
Quick facts
| Lead sponsor | Le Bonheur Children's Hospital |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 March 2010 |
| Primary completion | 1 May 2012 |
| Estimated completion | 1 November 2012 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Lacosamide (lacosamide) — full drug profile →
Conditions studied
- Epilepsy — all drugs for Epilepsy →
Sponsor
Le Bonheur Children's Hospital
Who can join
Adults 4 to 35, any sex, with Epilepsy. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
To evaluate the safety of IV Lacosamide given as a rapid infusion.
Time frame: one year
The safety of IV Lacosamide will be assessed in patients in whom parental administration of Lacosamide is warranted.
Sponsor's own description
To evaluate the safety of IV Lacosamide in children with partial-onset epilepsy, ages 4-35 years old, inclusive, who are either unable to take oral medication or require intravenous administration of IV Lacosamide.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Use of lacosamide in children with refractory epilepsy.
Buck ML, Goodkin HP. · · 2012 · cited 18× · PMID 23258963 · DOI 10.5863/1551-6776-17.3.211
Verify or expand the search:
- PubMed search for NCT00832884
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Lacosamide
Trials testing the same drug.
- NCT06969417 — Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia · NA · recruiting
- NCT05603702 — STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis · Phase 1 · recruiting
- NCT05510856 — Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Indu · Phase 4 · completed
- NCT05291455 — Lacosamide in Neonatal Status Epilepticus · Phase 3 · unknown
- NCT04627285 — A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) · Phase 3 · completed
Other recruiting trials for Epilepsy
Currently open trials in the same condition.
- NCT07095933 — The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy · EARLY_PHASE1 · recruiting
- NCT07224191 — Hippocampal Oscillations During Exploration · NA · recruiting
- NCT07219407 — A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures · Phase 2 · recruiting
- NCT07417280 — LIFUS For Neurological Disorders · NA · recruiting
- NCT07490769 — Levetiracetam Three Times Daily in Epilepsy · Phase 3 · recruiting
Other Le Bonheur Children's Hospital trials
Trials by the same sponsor.
- NCT04905563 — NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures · Phase 4 · terminated
- NCT04205877 — The U.S. PDA Registry · not yet recruiting
- NCT04222101 — Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy · NA · terminated
- NCT03897335 — Preventing Acute Kidney Injury (AKI) in Pediatric Patients · Phase 3 · unknown
- NCT03860012 — Folic Acid in Pediatric Inflammatory Bowel Disease · Phase 4 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00832884 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Le Bonheur Children's Hospital
- Last refreshed: 21 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00832884.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing