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NCT04222101
Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy
NA trial testing Oral glucose tolerance test in Cardiomyopathy, Dilated in 9 participants. Terminated before completion.
30 June 2021
Quick facts
| Lead sponsor | Le Bonheur Children's Hospital |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 9 |
| Start date | 7 October 2019 |
| Primary completion | 30 June 2021 |
| Estimated completion | 30 June 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Oral glucose tolerance test — full drug profile →
Conditions studied
- Cardiomyopathy, Dilated — all drugs for Cardiomyopathy, Dilated →
- Cardiomyopathy, Hypertrophic — all drugs for Cardiomyopathy, Hypertrophic →
- Insulin Resistance — all drugs for Insulin Resistance →
Sponsor
Le Bonheur Children's Hospital
Who can join
Adults 13 to 18, any sex, with Cardiomyopathy, Dilated or Cardiomyopathy, Hypertrophic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will investigate whether there is an association between insulin resistance and cardiac function in children with dilated or hypertrophic cardiomyopathy. This study will also investigate whether there is an association between FGF21 and cardiac function in children with dilated or hypertrophic cardiomyopathy and whether this is mediated through greater insulin resistance and/or through independent effects.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04222101
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Cardiomyopathy, Dilated
Currently open trials in the same condition.
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- NCT06091475 — Therapy to Maintain Remission in Dilated Cardiomyopathy · NA · recruiting
- NCT05981092 — A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM) · active not recruiting
- NCT05321875 — Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial) · Phase 3 · recruiting
- NCT07527715 — Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated Cardiomyopathy · recruiting
Other Le Bonheur Children's Hospital trials
Trials by the same sponsor.
- NCT04905563 — NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures · Phase 4 · terminated
- NCT04205877 — The U.S. PDA Registry · not yet recruiting
- NCT03897335 — Preventing Acute Kidney Injury (AKI) in Pediatric Patients · Phase 3 · unknown
- NCT03860012 — Folic Acid in Pediatric Inflammatory Bowel Disease · Phase 4 · unknown
- NCT03510091 — Video-Assisted Counseling for HPV Vaccination · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04222101 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Le Bonheur Children's Hospital
- Last refreshed: 20 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04222101.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing