Viral RNA-dependent RNA polymerase — Drug Target

All drugs that target Viral RNA-dependent RNA polymerase — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Nucleoside analog antiviral · nucleoside analog

Phase 3 pipeline (2)

• Molnupiravir (Esperavir) · Promomed, LLC · Nucleoside analog antiviral · Infectious Disease / Virology
  Molnupiravir is a nucleoside analog that induces viral mutagenesis by causing errors during viral RNA replication, leading to viral extinction.
• AV5080 · Viriom · Nucleoside analog antiviral · Infectious Disease / Virology
  AV5080 is a nucleoside analog that inhibits viral RNA-dependent RNA polymerase, blocking replication of RNA viruses.

Phase 1 pipeline (1)

• AT-527 single dose · Atea Pharmaceuticals, Inc. · nucleoside analog · Infectious Disease
  AT-527 is a nucleoside analog that inhibits viral RNA-dependent RNA polymerase, thereby blocking viral replication.