What drugs target Soluble guanylate cyclase?

5+ drugs target Soluble guanylate cyclase, including iNO, nitric oxide gel, Inomax, Inhaled Nitric Oxide (iNO) use.

What drug classes act on Soluble guanylate cyclase?

Drug classes acting on Soluble guanylate cyclase include Inhaled vasodilator, Topical vasodilator, Standardized Chemical Allergen [EPC], benzydamine.

5 drugs 4 marketed 1 in Phase 3

All drugs that target Soluble guanylate cyclase — marketed and clinical-stage. Includes 4 drug classes acting on this target.

iNO · Wake Forest University Health Sciences · Inhaled vasodilator · Critical Care / Respiratory
iNO is inhaled nitric oxide gas that dilates pulmonary blood vessels and improves oxygenation in patients with severe respiratory failure.
nitric oxide gel · China Medical University Hospital · Topical vasodilator · Dermatology / Wound Care
Nitric oxide gel delivers nitric oxide directly to tissue to promote vasodilation, improve blood flow, and enhance wound healing.
Inomax · Vero Biotech Inc · Standardized Chemical Allergen [EPC] · Cardiovascular
Inhaled Nitric Oxide (iNO) use · The University of Texas Health Science Center, Houston · Inhaled vasodilator · Pulmonary/Cardiovascular
Inhaled nitric oxide is a vasodilator gas that selectively relaxes pulmonary vascular smooth muscle to reduce pulmonary hypertension and improve oxygenation.

Benzidamine · benzydamine · Pain
Benzidamine works by activating soluble guanylate cyclase, an enzyme that produces cyclic guanosine monophosphate (cGMP), leading to pain relief.