S1PR1 — Drug Target
All drugs that target S1PR1 — marketed and clinical-stage. Includes 3 drug classes acting on this target.
Drug classes
S1P receptor modulator · Sphingosine-1-phosphate receptor 1 (S1PR1) modulator · S1PR1 inhibitor
Phase 3 pipeline (9)
- TVP-1012 · Takeda · S1P receptor modulator · Autoimmune diseases
TVP-1012 is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1). - SPMC 2 · Korea University Anam Hospital · Sphingosine-1-phosphate receptor 1 (S1PR1) modulator · Autoimmune diseases
SPMC 2 is a small molecule that targets the Sphingosine-1-phosphate receptor 1 (S1PR1) to modulate immune responses. - NPC-16 Continuous Dosing Regimen Group · Nobelpharma · S1P receptor modulator · Immunology
NPC-16 is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1) to modulate immune cell trafficking. - OPC-262 · Kyowa Kirin Co., Ltd. · S1PR1 inhibitor · Immunology
OPC-262 is a selective and potent inhibitor of the sphingosine-1-phosphate receptor 1 (S1PR1). - SPM 962 · Otsuka Pharmaceutical Co., Ltd. · S1P receptor modulator · Autoimmune diseases
SPM 962 is a selective, high-affinity, and orally bioavailable small molecule inhibitor of the sphingosine-1-phosphate receptor 1 (S1PR1). - Aplause® · Phytopharm Consulting Brazil · S1P receptor modulator · Immunology
Aplause is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1) to modulate immune responses. - allo-APZ2-OTS · RHEACELL GmbH & Co. KG · S1P receptor modulator · Autoimmune diseases
Allo-APZ2-OTS is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1). - NPC-16 Standard Dosing Regimen Group · Nobelpharma · S1P receptor modulator · Immunology
NPC-16 is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1) to modulate immune responses. - Fp MDPI · Teva Branded Pharmaceutical Products R&D, Inc. · S1P receptor modulator · Immunology
Fp MDPI is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1) to modulate immune cell trafficking.
Phase 2 pipeline (2)
- ABT-894 · AbbVie (prior sponsor, Abbott) · S1P receptor modulator · Multiple Sclerosis, Autoimmune Diseases
ABT-894 is a small molecule that targets the sphingosine-1-phosphate receptor 1 (S1PR1). - ABBV-552 · AbbVie · S1PR1 inhibitor · Autoimmune diseases
ABBV-552 is a small molecule inhibitor of the sphingosine-1-phosphate receptor 1 (S1PR1).