ATP-binding cassette sub-family G member 2 — Drug Target

All drugs that target ATP-binding cassette sub-family G member 2 — marketed and clinical-stage. Includes 7 drug classes acting on this target.

Drug classes

Cytochrome P450 3A Inhibitor [EPC] · Purine Antimetabolite [EPC] · Antimycobacterial · Echinocandin Antifungal · Azole Antifungal · topotecan · Antimalarial [EPC]

Marketed (8)

• Kaletra · Abbvie Deutschland Gmbh Co. Kg · Cytochrome P450 3A Inhibitor [EPC] · Immunology
  Kaletra blocks the protease enzyme, preventing the HIV virus from replicating.
• Imuran · Legacy Pharma · Purine Antimetabolite [EPC] · Immunology
• Lamprene · Novartis · Antimycobacterial · Metabolic
• Cancidas · Merck & Co. · Echinocandin Antifungal · Infectious Disease
  Cancidas works by inhibiting the synthesis of beta-1,6-glucan, a critical component of the fungal cell wall.
• Cresemba · Astellas Pharma · Azole Antifungal · Infectious Disease
  Isavuconazonium sulfate is a prodrug that converts to isavuconazole, an azole antifungal.
• Mycamine · Teva Pharms Usa Inc · Echinocandin Antifungal · Infectious Disease
• Nogitecan · Novartis · topotecan · Oncology
  Topotecan is a topoisomerase inhibitor that prevents DNA re-ligation, causing double-strand DNA damage.
• Mepron · Antimalarial [EPC] · Immunology
  Mepron works by inhibiting the electron transport chain in the mitochondria of Plasmodium parasites, ultimately leading to their death.