Alpha-2-delta subunit of voltage-gated calcium channels — Drug Target

All drugs that target Alpha-2-delta subunit of voltage-gated calcium channels — marketed and clinical-stage. Includes 4 drug classes acting on this target.

Drug classes

Gabapentinoid; anticonvulsant; anxiolytic · Anticonvulsant / Gabapentinoid · Anticonvulsant / Analgesic · Gabapentinoid; anticonvulsant; anxiolytic; analgesic

Marketed (3)

• Lyrica (pregabalin) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Gabapentinoid; anticonvulsant; anxiolytic · Neurology; Pain Management; Psychiatry
  Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
• stander treatment pregabalin · Hawler Medical University · Gabapentinoid; anticonvulsant; anxiolytic · Neurology; Pain Management; Psychiatry
  Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
• Pregabalin capsule · Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Gabapentinoid; anticonvulsant; anxiolytic · Neurology; Pain Management; Psychiatry
  Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.

Phase 3 pipeline (4)

• Gabapentin Pill · Shanghai Zhongshan Hospital · Anticonvulsant / Gabapentinoid · Neurology
  Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels, reducing the release of excitatory neurotransmitters in the nervous system.
• Gabapentin Extended Release tablets · Depomed · Anticonvulsant / Analgesic · Neurology / Pain Management
  Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
• Pregabalin Dose Level 1 · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Gabapentinoid; anticonvulsant; anxiolytic; analgesic · Neurology; Pain Management; Psychiatry
  Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
• Pregabalin Dose Level 2 · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Gabapentinoid; anticonvulsant; anxiolytic; analgesic · Neurology; Pain Management; Psychiatry
  Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.