ACE — Drug Target

All drugs that target ACE — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Thiazide Diuretic [EPC] · ACE inhibitor · ACE inhibitor and thiazide diuretic

Marketed (1)

• Microzide · Generic (originally Merck) · Thiazide Diuretic [EPC] · Cardiovascular
  Lisinopril inhibits ACE, reducing angiotensin II and aldosterone, leading to lower blood pressure.

Phase 3 pipeline (17)

• BR1019C-1 · Boryung Pharmaceutical Co., Ltd · ACE inhibitor · Cardiovascular
  BR1019C-1 is a small molecule drug that targets the renin-angiotensin system.
• DW-330SR2 · Daewon Pharmaceutical Co., Ltd. · ACE inhibitor · Cardiovascular
  DW-330SR2 is a small molecule that targets the renin-angiotensin system.
• BR1019A-1 · Boryung Pharmaceutical Co., Ltd · ACE inhibitor · Cardiovascular
  BR1019A-1 is a small molecule that targets the renin-angiotensin system.
• a simulated agent of Jitongning tablets · Tasly Pharmaceutical Group Co., Ltd · ACE inhibitor · Cardiovascular
  Jitongning tablets are a simulated agent that works by inhibiting the renin-angiotensin-aldosterone system (RAAS) to lower blood pressure.
• TDI01 suspension · Beijing Tide Pharmaceutical Co., Ltd · ACE inhibitor · Cardiovascular
  TDI01 suspension is a medication that targets the renin-angiotensin-aldosterone system (RAAS) to treat hypertension.
• NPF-08 （2-day split dose） · Nihon Pharmaceutical Co., Ltd · ACE inhibitor · Cardiovascular
  NPF-08 is a small molecule that targets the renin-angiotensin system to lower blood pressure.
• RBT-1 · Renibus Therapeutics, Inc. · ACE inhibitor · Cardiovascular
  RBT-1 is a small molecule that targets the renin-angiotensin system to treat hypertension.
• BR1018C-1 · Boryung Pharmaceutical Co., Ltd · ACE inhibitor · Cardiovascular
  BR1018C-1 is a small molecule that targets the renin-angiotensin system.
• BP101 · Ivix LLX · ACE inhibitor · Cardiovascular
  BP101 is a small molecule that targets the renin-angiotensin system to lower blood pressure.
• BPDO-1603 · Hyundai Pharmaceutical Co., LTD. · ACE inhibitor · Cardiovascular
  BPDO-1603 is a small molecule that targets the renin-angiotensin system to lower blood pressure.
• VGR-R01 · Shanghai Vitalgen BioPharma Co., Ltd. · ACE inhibitor · Cardiovascular
  VGR-R01 is a small molecule drug that targets the renin-angiotensin system.
• BR1018A-1 · Boryung Pharmaceutical Co., Ltd · ACE inhibitor · Cardiovascular
  BR1018A-1 is a small molecule drug that targets the renin-angiotensin system.
• GP40071 · Geropharm · ACE inhibitor · Cardiovascular
  GP40071 is a small molecule drug that targets the renin-angiotensin system.
• AG NPP709syrup · Ahn-Gook Pharmaceuticals Co.,Ltd · ACE inhibitor · Cardiovascular
  AG NPP709 syrup is a medication that targets the renin-angiotensin system to treat hypertension.
• T-2345 · Nephron Pharmaceuticals Corporation · ACE inhibitor · Cardiovascular
  T-2345 is a small molecule drug that targets the renin-angiotensin system.
• Ramipril and hydrochlorothiazide · Pfizer · ACE inhibitor and thiazide diuretic · Cardiovascular
  Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to angiotensin II, while hydrochlorothiazide is a thiazide diuretic that increases urine production.
• Product CM9241GRU · Ache Laboratorios Farmaceuticos S.A. · ACE inhibitor · Cardiovascular
  CM9241GRU is a drug that targets the renin-angiotensin system.

Phase 2 pipeline (3)

• BP1.4979 active drug · Bioprojet · ACE inhibitor · Cardiovascular
  BP1.4979 is a small molecule drug that targets the renin-angiotensin system.
• BP-C2 · Meddoc · ACE inhibitor · Cardiovascular
  BP-C2 is a small molecule that targets the renin-angiotensin system to lower blood pressure.
• Enalapril Orodispersible Minitablet · Ethicare GmbH · ACE inhibitor · Cardiovascular
  Enalapril inhibits angiotensin-converting enzyme (ACE), reducing the production of angiotensin II and aldosterone, leading to vasodilation and decreased blood pressure.