5-HT2A — Drug Target

All drugs that target 5-HT2A — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Serotonin receptor agonist · Serotonin receptor antagonist · Serotonin 5-HT2A receptor agonist

Phase 3 pipeline (2)

• Usual DMT continuation · University Hospital, Strasbourg, France · Serotonin receptor agonist · Psychiatry
  DMT acts as a potent agonist at the serotonin 5-HT2A receptor.
• AD-227B · Addpharma Inc. · Serotonin receptor antagonist · Psychiatry
  AD-227B is a small molecule that targets the serotonin receptor 5-HT2A.

Phase 2 pipeline (3)

• ATI-502 · Aclaris Therapeutics, Inc. · Serotonin receptor antagonist · Neurology
  ATI-502 is a small molecule inhibitor of the serotonin receptor 5-HT2A.
• AP-472 · Appello Pharmaceuticals, Inc. · Serotonin receptor antagonist · Psychiatry
  AP-472 is a small molecule that targets the serotonin receptor 5-HT2A.
• CYB004 · Cybin IRL Limited · Serotonin 5-HT2A receptor agonist · Psychiatry
  CYB004 is a psychedelic compound that acts as a serotonin 5-HT2A receptor agonist.