Last reviewed · How we verify

Usual DMT continuation

University Hospital, Strasbourg, France · Phase 3 active Small molecule

DMT acts as a potent agonist at the serotonin 5-HT2A receptor.

DMT acts as a potent agonist at the serotonin 5-HT2A receptor. Used for Treatment-resistant depression.

At a glance

Generic nameUsual DMT continuation
SponsorUniversity Hospital, Strasbourg, France
Drug classSerotonin receptor agonist
Target5-HT2A
ModalitySmall molecule
Therapeutic areaPsychiatry
PhasePhase 3

Mechanism of action

DMT's mechanism of action primarily involves the activation of the 5-HT2A receptor, which is a subtype of the serotonin receptor. This activation can lead to altered perception, mood changes, and other psychoactive effects. The exact mechanisms underlying DMT's therapeutic effects in the context of Usual DMT continuation are not well understood.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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