{"id":"usual-dmt-continuation","safety":{"commonSideEffects":[{"rate":"10-30%","effect":"Hallucinations"},{"rate":"10-20%","effect":"Anxiety"},{"rate":"5-15%","effect":"Nausea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"DMT's mechanism of action primarily involves the activation of the 5-HT2A receptor, which is a subtype of the serotonin receptor. This activation can lead to altered perception, mood changes, and other psychoactive effects. The exact mechanisms underlying DMT's therapeutic effects in the context of Usual DMT continuation are not well understood.","oneSentence":"DMT acts as a potent agonist at the serotonin 5-HT2A receptor.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:53:50.076Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment-resistant depression"}]},"trialDetails":[{"nctId":"NCT06663189","phase":"PHASE3","title":"Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis)","status":"NOT_YET_RECRUITING","sponsor":"University Hospital, Strasbourg, France","startDate":"2025-01","conditions":"Relapsing-remitting Multiple Sclerosis (RRMS)","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Usual DMT continuation","genericName":"Usual DMT continuation","companyName":"University Hospital, Strasbourg, France","companyId":"university-hospital-strasbourg-france","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DMT acts as a potent agonist at the serotonin 5-HT2A receptor. Used for Treatment-resistant depression.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}