Is there a generic for Celebrex?

Yes — 6 approved generic versions of Celebrex (celecoxib) are tracked in our index. Generic substitution is typically automatic at the pharmacy unless the prescriber writes "dispense as written."

How much cheaper is generic celecoxib?

Generic small-molecule drugs typically launch at 60-80% discount to the originator. After multiple manufacturers enter the market (12-24 months post-cliff), prices drop further to 85-95% below originator. Your insurance copay may not reflect the full savings — check the cash price too.

Are generics as effective as the brand?

For small-molecule drugs: yes. Generics are required to demonstrate bioequivalence — identical active ingredient, same dose, same route, same indication. Pharmacokinetic equivalence within tight bounds (±20% AUC + Cmax). Most patients can switch without clinical effect.

When did Celebrex go generic?

Generic celecoxib entered the US market when the originator's exclusivity expired. See the patent timeline below for specific dates.

Last reviewed 2026-06-10 · How we verify

Celebrex generic

Complete generic competition for Celebrex (celecoxib): 6 approved generics across manufacturers, 0 filed under FDA review. 6 active patents remain. Sourced from FDA Orange Book + USPTO.

6 approved generics 6 active patents

About Celebrex

Celebrex (celecoxib) — originally marketed by Pfizer Inc. (originally Searle/Pharmacia). Class: Nonsteroidal Anti-inflammatory Drug [EPC]. First approved 1998-12-31.

Approved generic versions (6)

Generic	Manufacturer	Phase	First approval
CELECOXIB		marketed	1998-01-01
Celecoxib 400 milligrams	Pfizer	marketed
Celecoxib 100 mg	Charles University, Czech Republic	marketed
Celecoxib 200 milligrams	Pfizer	marketed
Celecoxib capsule	Xuhui Central Hospital, Shanghai	marketed
Celecoxib (Celebrex)	National Eye Institute (NEI)	marketed

Originator patent timeline

Active patents (6)

2036-05-27 — 10722456 · Formulation · US
2036-05-27 — 10799517 · Formulation · US
2036-05-27 — 9949990 · Formulation · US
2036-05-27 — 9795620 · Formulation · US
2036-05-27 — 9572819 · Formulation · US
2036-05-27 — 10376527 · Formulation · US

Expired patents (0)

No expired patents tracked.

How small-molecule generic approval works

Generic versions of small-molecule drugs are approved by the FDA via the Abbreviated New Drug Application (ANDA) pathway under the Hatch-Waxman Act of 1984. Sponsors must demonstrate bioequivalence (pharmacokinetic equivalence within tight bounds) and identical chemical composition — no clinical trials in patients are required. Approval typically takes 18-24 months.

This is different from biosimilars for biologic drugs, which use the more complex 351(k) BLA pathway and typically achieve smaller (15-35%) discounts vs the originator. Small-molecule generics typically launch at 60-80% discount, dropping to 85-95% within 2 years.

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Celebrex full drug profile
Biosimilar tracker (for biologic drugs)
Patent cliff tracker
Biosimilar vs generic — what's the difference?

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing