Generic entry timeline

Cipro generics — when can they launch?

Cipro (Ciprofloxacin) · Alk Abello · 8 active US patents · 0 expired

Earliest patent expiry
2029-04-21
3 years remaining
Full patent estate to
2038-11-27
complete protection through 2038
FDA approval
1987
Alk Abello

Where Cipro sits in the generic timeline

Imminent generic cliff: earliest active US patent for Cipro expires in 2029 (~3 years from today). ANDA filers are likely already preparing Paragraph IV certifications. Expect first-filer 180-day exclusivity competition imminently.

Under US Hatch-Waxman, a generic enters via an ANDA (Abbreviated New Drug Application) and may file with one of four Paragraph IV certifications attacking the brand's listed patents. If the brand sues within 45 days, a 30-month FDA approval stay is triggered. First Para IV filer typically gets 180-day market exclusivity.

Patent estate by type — active patents

Method-of-use patents only carve out specific indications; generics can launch with a "skinny label" omitting those uses. Composition-of-matter patents block the molecule itself.

  • Formulation — 4 patents
  • Method of Use — 4 patents

FDA U-codes carved out by Cipro patents

Method-of-use patents are listed against specific FDA Patent Use Codes ("U-codes") representing carved-out indications. Generics can launch with a label that omits these uses.

U-codeDescription
U-1793(no description)
U-2252(no description)
U-1792(no description)

Sample patent estate

Showing 6 of 8 active US patents. View full estate on the Cipro drug page →

  • US11369566 Formulation · expires 2029-04-21
    This patent protects controlled release compositions and methods for treating otic disorders with antimicrobial agents administered directly to the affected area.
    USPTO title: Controlled release antimicrobial compositions and methods for the treatment of otic disorders
  • US9205048 Method of Use · expires 2029-04-21
    This patent protects methods and compositions for treating otic diseases or conditions using antimicrobial agents applied directly to the affected area.
    USPTO title: Controlled release antimicrobial compositions and methods for the treatment of otic disorders
  • US9603796 Method of Use · expires 2029-04-21
    This patent protects methods and compositions for treating otic diseases or conditions using antimicrobial agents applied directly to the affected area.
    USPTO title: Controlled release antimicrobial compositions and methods for the treatment of otic disorders
  • US9233068 Formulation · expires 2029-12-11
    This patent protects controlled release compositions and methods for treating otic diseases or conditions with antimicrobial agents administered directly to the affected ear area.
    USPTO title: Controlled release antimicrobial compositions and methods for the treatment of OTIC disorders
  • US8318817 Method of Use · expires 2030-04-27
    This patent protects methods and compositions for treating otic diseases or conditions using antimicrobial agents applied directly to the affected area.
    USPTO title: Controlled release antimicrobial compositions and methods for the treatment of otic disorders
  • US9220796 Formulation · expires 2035-07-01
    This patent protects methods for making sterilized ciprofloxacin compositions, including otic formulations, through a specific heating and cooling process.
    USPTO title: Sterilization of ciprofloxacin composition

Sources

Patent term extensions (PTR, pediatric exclusivity), Hatch-Waxman 30-month stays, and FDA regulatory exclusivity (NCE/ODE/PED) may shift the effective generic entry date. Not legal advice.

Get generic entry alerts

Free Pharma CI alerts on Cipro — get notified the moment an ANDA Paragraph IV certification is filed, a 30-month stay is triggered, or a generic launches. First 2 drugs free.

Subscribe free →