US Patent

US9220796 — Sterilization of ciprofloxacin composition

Formulation · Assigned to Otonomy Inc · Expires 2035-07-01 · 9y remaining

Vulnerability score 42/100 Strong — defensible against typical IPR challenges

What this patent protects

This patent protects methods for making sterilized ciprofloxacin compositions, including otic formulations, through a specific heating and cooling process.

USPTO Abstract

Disclosed herein are methods of making sterilized ciprofloxacin compositions. In some embodiments, the method includes the steps of: (a) forming an aqueous suspension comprising ciprofloxacin particles; (b) heating the aqueous suspension comprising ciprofloxacin particles at a temperature range of from about 100° C. to about 120° C.; and (c) allowing the aqueous suspension comprising ciprofloxacin particles to cool down. Also described herein are otic formulations containing ciprofloxacin formed by the disclosed methods, and therapeutic use of such otic formulation for providing sustained release of ciprofloxacin into the ear for treating various otic disorders and conditions.

Drugs covered by this patent

Patent Metadata

Patent number
US9220796
Jurisdiction
US
Classification
Formulation
Expires
2035-07-01
Drug substance claim
No
Drug product claim
Yes
Assignee
Otonomy Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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