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Yellow fever vaccine, Institut Pasteur
The vaccine stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus through a live attenuated viral strain.
The vaccine stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus through a live attenuated viral strain. Used for Prevention of yellow fever in travelers to endemic regions, Prevention of yellow fever in at-risk populations in endemic areas.
At a glance
| Generic name | Yellow fever vaccine, Institut Pasteur |
|---|---|
| Also known as | Children sub-study |
| Sponsor | University of Oxford |
| Drug class | Live attenuated vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | FDA-approved |
Mechanism of action
Yellow fever vaccine (Institut Pasteur strain) contains a weakened live yellow fever virus that replicates in vaccinated individuals without causing disease. This triggers both humoral (antibody) and cell-mediated immune responses, providing protective immunity against infection with wild-type yellow fever virus. A single dose typically confers lifelong immunity in most recipients.
Approved indications
- Prevention of yellow fever in travelers to endemic regions
- Prevention of yellow fever in at-risk populations in endemic areas
Common side effects
- Headache
- Myalgia
- Fever
- Injection site reaction
- Fatigue
Key clinical trials
- Non- Inferiority Fractional-doses Trial for Yellow Fever Vaccine (PHASE4)
- Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Yellow fever vaccine, Institut Pasteur CI brief — competitive landscape report
- Yellow fever vaccine, Institut Pasteur updates RSS · CI watch RSS
- University of Oxford portfolio CI