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Systane (r) Ultra

ORA, Inc. · FDA-approved active Small molecule

Systane Ultra is a lubricating eye drop that provides sustained moisture and relief to the ocular surface by forming a protective film.

Systane Ultra is a lubricating eye drop that provides sustained moisture and relief to the ocular surface by forming a protective film. Used for Dry eye syndrome / dry eye disease.

At a glance

Generic nameSystane (r) Ultra
Also known asSystane Ultra
SponsorORA, Inc.
Drug classArtificial tear / ocular lubricant
ModalitySmall molecule
Therapeutic areaOphthalmology
PhaseFDA-approved

Mechanism of action

Systane Ultra contains a proprietary blend of lubricants including polyethylene glycol 400 and propylene glycol, along with the gelling agent hydroxypropyl guar, which creates a sustained-release formulation. The formula adheres to the eye surface and provides long-lasting lubrication and protection for dry eye symptoms. It works through mechanical hydration and surface protection rather than targeting a specific molecular receptor.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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