Who are Systane (r) Ultra's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): TJO-018 (HA 0.15%), Retaine™, TheraTears® Lubricant Eye Drop, Systane Ultra UD, Cationorm single-dose eye drop, methylcellulose 0.5%.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Systane (r) Ultra — Competitive Intelligence Brief

Systane (r) Ultra (Systane (r) Ultra) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Artificial tear / ocular lubricant. Area: Ophthalmology.

marketed Artificial tear / ocular lubricant Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Systane (r) Ultra (Systane (r) Ultra) — ORA, Inc.. Systane Ultra is a lubricating eye drop that provides sustained moisture and relief to the ocular surface by forming a protective film.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Systane (r) Ultra TARGET	Systane (r) Ultra	ORA, Inc.	marketed	Artificial tear / ocular lubricant
TJO-018 (HA 0.15%)	TJO-018 (HA 0.15%)	Taejoon Pharmaceutical Co., Ltd.	marketed	Artificial tear / Ocular lubricant	Ocular surface (non-receptor mediated)
Retaine™	Retaine™	Ocusoft, Inc.	marketed	Artificial tear / ocular lubricant
TheraTears® Lubricant Eye Drop	TheraTears® Lubricant Eye Drop	University of Waterloo	marketed	Artificial tear / Ocular lubricant
Systane Ultra UD	Systane Ultra UD	Ocuwize LTD	marketed	Artificial tear / Ocular lubricant
Cationorm single-dose eye drop	Cationorm single-dose eye drop	Nguyen Viet Giap	marketed	Artificial tear / ocular lubricant
methylcellulose 0.5%	methylcellulose 0.5%	Clinica Oftamologica Zona Sul	marketed	Artificial tear / Ocular lubricant

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Artificial tear / ocular lubricant class)

Allergan · 2 drugs in this class
Chang Gung Memorial Hospital · 1 drug in this class
Guang'anmen Hospital of China Academy of Chinese Medical Sciences · 1 drug in this class
Medical University of Vienna · 1 drug in this class
Nguyen Viet Giap · 1 drug in this class
ORA, Inc. · 1 drug in this class
Ocusoft, Inc. · 1 drug in this class
The Mentholatum Company · 1 drug in this class
Tianjin Eye Hospital · 1 drug in this class
University of Sao Paulo · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Systane (r) Ultra — Competitive Intelligence Brief. https://druglandscape.com/ci/systane-r-ultra. Accessed 2026-05-16.

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