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Supine hyperpolarized 3 helium gas scan
Hyperpolarized helium-3 gas imaging is a diagnostic imaging technique that uses polarized helium-3 atoms to visualize ventilation patterns and lung function in real-time.
Hyperpolarized helium-3 gas imaging is a diagnostic imaging technique that uses polarized helium-3 atoms to visualize ventilation patterns and lung function in real-time. Used for Functional lung imaging for assessment of ventilation defects, Evaluation of chronic obstructive pulmonary disease (COPD), Assessment of asthma and other obstructive airway diseases.
At a glance
| Generic name | Supine hyperpolarized 3 helium gas scan |
|---|---|
| Also known as | Supine MRI scan with contrast |
| Sponsor | Eric A. Hoffman |
| Modality | Small molecule |
| Therapeutic area | Pulmonology / Respiratory |
| Phase | FDA-approved |
Mechanism of action
The helium-3 nuclei are hyperpolarized to enhance their magnetic resonance signal, allowing detailed visualization of gas distribution throughout the lungs during breathing. This non-invasive imaging modality can detect regional ventilation defects and abnormalities in lung function that may not be visible on conventional imaging, providing functional assessment of pulmonary disease.
Approved indications
- Functional lung imaging for assessment of ventilation defects
- Evaluation of chronic obstructive pulmonary disease (COPD)
- Assessment of asthma and other obstructive airway diseases
Common side effects
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Supine hyperpolarized 3 helium gas scan CI brief — competitive landscape report
- Supine hyperpolarized 3 helium gas scan updates RSS · CI watch RSS
- Eric A. Hoffman portfolio CI