{"id":"supine-hyperpolarized-3-helium-gas-scan","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The helium-3 nuclei are hyperpolarized to enhance their magnetic resonance signal, allowing detailed visualization of gas distribution throughout the lungs during breathing. This non-invasive imaging modality can detect regional ventilation defects and abnormalities in lung function that may not be visible on conventional imaging, providing functional assessment of pulmonary disease.","oneSentence":"Hyperpolarized helium-3 gas imaging is a diagnostic imaging technique that uses polarized helium-3 atoms to visualize ventilation patterns and lung function in real-time.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:10:18.862Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Functional lung imaging for assessment of ventilation defects"},{"name":"Evaluation of chronic obstructive pulmonary disease (COPD)"},{"name":"Assessment of asthma and other obstructive airway diseases"}]},"trialDetails":[{"nctId":"NCT03776747","phase":"PHASE4","title":"Repeatability in Hyperpolarized 3-Helium With MRI","status":"COMPLETED","sponsor":"Eric A. Hoffman","startDate":"2008-07-22","conditions":"Radiation Exposure","enrollment":18}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Supine MRI scan with contrast"],"phase":"marketed","status":"active","brandName":"Supine hyperpolarized 3 helium gas scan","genericName":"Supine hyperpolarized 3 helium gas scan","companyName":"Eric A. Hoffman","companyId":"eric-a-hoffman","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Hyperpolarized helium-3 gas imaging is a diagnostic imaging technique that uses polarized helium-3 atoms to visualize ventilation patterns and lung function in real-time. Used for Functional lung imaging for assessment of ventilation defects, Evaluation of chronic obstructive pulmonary disease (COPD), Assessment of asthma and other obstructive airway diseases.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}