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sulfalene-pyrimethamine plus amodiaquine
sulfalene-pyrimethamine plus amodiaquine is a Antimalarial Small molecule drug developed by London School of Hygiene and Tropical Medicine. It is currently in Phase 3 development for Treatment of uncomplicated malaria. Also known as: Dualkin.
Sulfalene-pyrimethamine plus amodiaquine is an antimalarial combination that works by inhibiting the growth of the malaria parasite.
Sulfalene-pyrimethamine plus amodiaquine is an antimalarial combination that works by inhibiting the growth of the malaria parasite. Used for Treatment of uncomplicated malaria.
At a glance
| Generic name | sulfalene-pyrimethamine plus amodiaquine |
|---|---|
| Also known as | Dualkin |
| Sponsor | London School of Hygiene and Tropical Medicine |
| Drug class | Antimalarial |
| Modality | Small molecule |
| Therapeutic area | Infectious Diseases |
| Phase | Phase 3 |
Mechanism of action
Sulfalene-pyrimethamine is a combination of sulfadoxine and pyrimethamine, which are sulfonamide and dihydrofolate reductase inhibitors, respectively. Amodiaquine is a 4-aminoquinoline antimalarial that works by interfering with the parasite's heme detoxification pathway. Together, they provide a synergistic effect against the malaria parasite.
Approved indications
- Treatment of uncomplicated malaria
Common side effects
- Nausea
- Vomiting
- Diarrhea
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- sulfalene-pyrimethamine plus amodiaquine CI brief — competitive landscape report
- sulfalene-pyrimethamine plus amodiaquine updates RSS · CI watch RSS
- London School of Hygiene and Tropical Medicine portfolio CI
Frequently asked questions about sulfalene-pyrimethamine plus amodiaquine
What is sulfalene-pyrimethamine plus amodiaquine?
How does sulfalene-pyrimethamine plus amodiaquine work?
What is sulfalene-pyrimethamine plus amodiaquine used for?
Who makes sulfalene-pyrimethamine plus amodiaquine?
Is sulfalene-pyrimethamine plus amodiaquine also known as anything else?
What drug class is sulfalene-pyrimethamine plus amodiaquine in?
What development phase is sulfalene-pyrimethamine plus amodiaquine in?
What are the side effects of sulfalene-pyrimethamine plus amodiaquine?
Related
- Drug class: All Antimalarial drugs
- Manufacturer: London School of Hygiene and Tropical Medicine — full pipeline
- Therapeutic area: All drugs in Infectious Diseases
- Indication: Drugs for Treatment of uncomplicated malaria
- Also known as: Dualkin
- Compare: sulfalene-pyrimethamine plus amodiaquine vs similar drugs
- Pricing: sulfalene-pyrimethamine plus amodiaquine cost, discount & access