Last reviewed 2026-04-23 · How we verify

SENNA+CASSIA(Naturetti)

Senna and Cassia are anthraquinone laxatives that stimulate bowel movements by increasing water and electrolyte secretion into the intestinal lumen.

Senna and Cassia are anthraquinone laxatives that stimulate bowel movements by increasing water and electrolyte secretion into the intestinal lumen. Used for Constipation.

At a glance

Mechanism of action

Senna and Cassia work by activating the muscarinic receptors in the intestinal smooth muscle, leading to increased peristalsis and bowel movements. This action is thought to be mediated by the anthraquinone glycosides present in these plants, which are metabolized to anthranoid compounds that stimulate the muscarinic receptors.

Approved indications

• Constipation

Common side effects

• Diarrhea
• Abdominal cramps
• Nausea

Key clinical trials

• Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment. (PHASE3)
• Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC). (PHASE3)

Primary sources

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