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Prilocaine HCl % 2 injectable solution
Prilocaine HCl % 2 injectable solution is a Local anesthetic (amide class) Small molecule drug developed by Bozyaka Training and Research Hospital. It is currently FDA-approved for Local infiltration anesthesia, Nerve blocks, Topical anesthesia for minor surgical and dental procedures. Also known as: priloc %2.
Prilocaine HCl is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.
Prilocaine HCl is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses. Used for Local infiltration anesthesia, Nerve blocks, Topical anesthesia for minor surgical and dental procedures.
At a glance
| Generic name | Prilocaine HCl % 2 injectable solution |
|---|---|
| Also known as | priloc %2 |
| Sponsor | Bozyaka Training and Research Hospital |
| Drug class | Local anesthetic (amide class) |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Prilocaine is an amide-type local anesthetic that reversibly inhibits sodium influx into nerve fibers, thereby stabilizing the neuronal membrane and preventing depolarization. This action blocks the generation and propagation of action potentials in sensory and motor nerves, producing localized anesthesia. It is commonly used for infiltration anesthesia, nerve blocks, and topical anesthesia in clinical settings.
Approved indications
- Local infiltration anesthesia
- Nerve blocks
- Topical anesthesia for minor surgical and dental procedures
Common side effects
- Methemoglobinemia
- Allergic reactions
- Systemic toxicity (CNS and cardiovascular effects at high doses)
- Local reactions at injection site
Key clinical trials
- Does Botulinum Toxin Type-A Injection an Effective Way of Relieving Pain in Myofascial Pain Syndrome Patients or Not (NA)
- Comparison of Different Approaches for Supraclavicular Block and Their Effects on Diaphragm Muscle Function (PHASE4)
- Selective Spinal Anaesthesia With Hyperbaric Prilocain With 2%Provides Better Perioperative Hemodynamic Stability for Patients With Peripheral Vascular Disease and Cardiac Dysfunction in Lower Limb Surgery (NA)
- Comparison of Infraclavicular And Supraclavicular Block (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Prilocaine HCl % 2 injectable solution CI brief — competitive landscape report
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- Bozyaka Training and Research Hospital portfolio CI
Frequently asked questions about Prilocaine HCl % 2 injectable solution
What is Prilocaine HCl % 2 injectable solution?
How does Prilocaine HCl % 2 injectable solution work?
What is Prilocaine HCl % 2 injectable solution used for?
Who makes Prilocaine HCl % 2 injectable solution?
Is Prilocaine HCl % 2 injectable solution also known as anything else?
What drug class is Prilocaine HCl % 2 injectable solution in?
What development phase is Prilocaine HCl % 2 injectable solution in?
What are the side effects of Prilocaine HCl % 2 injectable solution?
What does Prilocaine HCl % 2 injectable solution target?
Related
- Drug class: All Local anesthetic (amide class) drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Bozyaka Training and Research Hospital — full pipeline
- Therapeutic area: All drugs in Anesthesia
- Indication: Drugs for Local infiltration anesthesia
- Indication: Drugs for Nerve blocks
- Indication: Drugs for Topical anesthesia for minor surgical and dental procedures
- Also known as: priloc %2
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing