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preservative-free 0.15% HA
Hyaluronic acid (HA) lubricates and protects the ocular surface by mimicking natural tear film components.
Hyaluronic acid (HA) lubricates and protects the ocular surface by mimicking natural tear film components. Used for Dry eye syndrome / keratoconjunctivitis sicca, Ocular surface protection and lubrication.
At a glance
| Generic name | preservative-free 0.15% HA |
|---|---|
| Also known as | Per-Young Eye Drops |
| Sponsor | Chang Gung Memorial Hospital |
| Drug class | Artificial tear / ocular lubricant |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
Hyaluronic acid is a naturally occurring polysaccharide that acts as a viscoelastic agent, providing lubrication and moisture retention on the cornea and conjunctiva. The preservative-free formulation reduces irritation from chemical preservatives, making it suitable for sensitive eyes or frequent use. HA forms a protective hydrophilic layer that reduces friction and promotes corneal healing.
Approved indications
- Dry eye syndrome / keratoconjunctivitis sicca
- Ocular surface protection and lubrication
Common side effects
- Transient blurred vision
- Mild ocular irritation
- Conjunctival hyperemia
Key clinical trials
- Evaluation of Dexpanthenol and Hyaluronic Acid Eye Drops on Corneal Epithelialization After Trans Epithelial PRK (PHASE4)
- Effect of Preservative-free Low-dose Hyaluronic Acid-containing Salt Solution on Dry Eye Disease (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- preservative-free 0.15% HA CI brief — competitive landscape report
- preservative-free 0.15% HA updates RSS · CI watch RSS
- Chang Gung Memorial Hospital portfolio CI