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Postop oral oxycodone
Postop oral oxycodone is a Opioid analgesic Small molecule drug developed by AdventHealth. It is currently FDA-approved for Postoperative pain management (acute pain following surgery). Also known as: Roxicodone.
Oxycodone binds to opioid receptors in the central nervous system to block pain signal transmission and provide analgesia.
Postoperative oral oxycodone is used to treat conditions such as pancreatic cancer, surgery complications, pancreatic fistula, delayed gastric emptying, and pancreatic hemorrhage. As a mu opioid receptor agonist, it works by activating the mu-type opioid receptor, which is a small molecule drug that belongs to the agonist class.
At a glance
| Generic name | Postop oral oxycodone |
|---|---|
| Also known as | Roxicodone |
| Sponsor | AdventHealth |
| Drug class | Opioid analgesic |
| Target | Mu (μ) opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Oxycodone is a semi-synthetic opioid agonist that binds primarily to mu (μ) opioid receptors in the brain and spinal cord, reducing the perception and emotional response to pain. In the postoperative setting, it is used for moderate to severe acute pain management following surgery. The drug crosses the blood-brain barrier and modulates pain signaling pathways, providing rapid onset analgesia when administered orally.
Approved indications
- Postoperative pain management (acute pain following surgery)
Common side effects
- Constipation
- Nausea
- Dizziness
- Drowsiness
- Vomiting
- Pruritus
- Respiratory depression
Key clinical trials
- Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (NA)
- Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty (PHASE4)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery (NA)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery in Gynecologic Oncology (NA)
- The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Laparoscopic Surgery (NA)
- Open-label Placebo for Pain Management in Adolescents and Young Adults Undergoing Bernese Periacetabular Osteotomy (NA)
- Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy (PHASE2, PHASE3)
- The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Postop oral oxycodone CI brief — competitive landscape report
- Postop oral oxycodone updates RSS · CI watch RSS
- AdventHealth portfolio CI
Frequently asked questions about Postop oral oxycodone
What is Postop oral oxycodone?
How does Postop oral oxycodone work?
What is Postop oral oxycodone used for?
Who makes Postop oral oxycodone?
Is Postop oral oxycodone also known as anything else?
What drug class is Postop oral oxycodone in?
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What are the side effects of Postop oral oxycodone?
What does Postop oral oxycodone target?
Related
- Drug class: All Opioid analgesic drugs
- Target: All drugs targeting Mu (μ) opioid receptor
- Manufacturer: AdventHealth — full pipeline
- Therapeutic area: All drugs in Pain Management
- Indication: Drugs for Postoperative pain management (acute pain following surgery)
- Also known as: Roxicodone
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing