Last reviewed · How we verify
Placebo capsule (Vitamin K1)
Placebo capsule (Vitamin K1) is a Vitamin/Nutritional supplement Small molecule drug developed by University of Sydney. It is currently in Phase 3 development for Placebo control in Phase 3 clinical trial (specific indication unknown). Also known as: Matching placebo capsule.
Vitamin K1 acts as a cofactor for gamma-glutamyl carboxylase, enabling the synthesis of vitamin K-dependent clotting factors (II, VII, IX, X) and other regulatory proteins.
Vitamin K1 acts as a cofactor for gamma-glutamyl carboxylase, enabling the synthesis of vitamin K-dependent clotting factors (II, VII, IX, X) and other regulatory proteins. Used for Placebo control in Phase 3 clinical trial (specific indication unknown).
At a glance
| Generic name | Placebo capsule (Vitamin K1) |
|---|---|
| Also known as | Matching placebo capsule |
| Sponsor | University of Sydney |
| Drug class | Vitamin/Nutritional supplement |
| Target | Gamma-glutamyl carboxylase (GGCX) |
| Modality | Small molecule |
| Therapeutic area | Hematology/Coagulation |
| Phase | Phase 3 |
Mechanism of action
Vitamin K1 (phylloquinone) is an essential cofactor required for the post-translational carboxylation of glutamic acid residues in vitamin K-dependent proteins. This carboxylation is critical for the activation of coagulation factors II, VII, IX, and X, as well as anticoagulant proteins C and S. In this Phase 3 trial context, the placebo capsule containing Vitamin K1 serves as the control arm, providing baseline nutritional vitamin K supplementation.
Approved indications
- Placebo control in Phase 3 clinical trial (specific indication unknown)
Common side effects
- Adverse events unlikely at nutritional doses
Key clinical trials
- Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis: (NA)
- Better Evidence and Translation for Calciphylaxis (PHASE3)
- Dietary Supplements for COVID-19 (PHASE3)
- Biocomparison Study (NA)
- The Effect of Vitamin K Supplementation on Bone Health in Adult Crohn's Disease Patients (PHASE4)
- Investigation of the Effect of BONISTEIN(R) Bone Blend on Bone Mineral Density/Content and Biomarkers of Bone Health (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Placebo capsule (Vitamin K1) CI brief — competitive landscape report
- Placebo capsule (Vitamin K1) updates RSS · CI watch RSS
- University of Sydney portfolio CI
Frequently asked questions about Placebo capsule (Vitamin K1)
What is Placebo capsule (Vitamin K1)?
How does Placebo capsule (Vitamin K1) work?
What is Placebo capsule (Vitamin K1) used for?
Who makes Placebo capsule (Vitamin K1)?
Is Placebo capsule (Vitamin K1) also known as anything else?
What drug class is Placebo capsule (Vitamin K1) in?
What development phase is Placebo capsule (Vitamin K1) in?
What are the side effects of Placebo capsule (Vitamin K1)?
What does Placebo capsule (Vitamin K1) target?
Related
- Drug class: All Vitamin/Nutritional supplement drugs
- Target: All drugs targeting Gamma-glutamyl carboxylase (GGCX)
- Manufacturer: University of Sydney — full pipeline
- Therapeutic area: All drugs in Hematology/Coagulation
- Indication: Drugs for Placebo control in Phase 3 clinical trial (specific indication unknown)
- Also known as: Matching placebo capsule
- Compare: Placebo capsule (Vitamin K1) vs similar drugs
- Pricing: Placebo capsule (Vitamin K1) cost, discount & access