Last reviewed 2026-04-20 · How we verify

Pentoxiverine (pentoxyverine)

FDA-approved active Quality 23/100

Pentoxiverine (generic name: pentoxyverine) is a Central Nervous System Stimulant [EPC] drug. It is currently FDA-approved for Allergic rhinitis, Common cold, Cough.

At a glance

Generic name	pentoxyverine
Drug class	Central Nervous System Stimulant [EPC]
Target	Sigma non-opioid intracellular receptor 1
Therapeutic area	Respiratory
Phase	FDA-approved

Approved indications

Allergic rhinitis
Common cold
Cough
Nasal congestion
Nasal discharge
Rhinitis
Vasomotor rhinitis

Common side effects

No common side effects on file.

Key clinical trials

Tolerability and Potential ECG Effects After a Single Oral Dose of Pentoxyverine Citrate in Healthy Male and Female Volunteers (PHASE1)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Pentoxiverine CI brief — competitive landscape report
Pentoxiverine updates RSS · CI watch RSS
portfolio CI

Frequently asked questions about Pentoxiverine

What is Pentoxiverine?

Pentoxiverine (pentoxyverine) is a Central Nervous System Stimulant [EPC] drug, indicated for Allergic rhinitis, Common cold, Cough.

What is Pentoxiverine used for?

Pentoxiverine is indicated for Allergic rhinitis, Common cold, Cough, Nasal congestion, Nasal discharge.

What is the generic name of Pentoxiverine?

pentoxyverine is the generic (nonproprietary) name of Pentoxiverine.

What drug class is Pentoxiverine in?

Pentoxiverine belongs to the Central Nervous System Stimulant [EPC] class. See all Central Nervous System Stimulant [EPC] drugs at /class/central-nervous-system-stimulant-epc.

What development phase is Pentoxiverine in?

Pentoxiverine is FDA-approved (marketed).

What does Pentoxiverine target?

Pentoxiverine targets Sigma non-opioid intracellular receptor 1 and is a Central Nervous System Stimulant [EPC].

Drug class: All Central Nervous System Stimulant [EPC] drugs
Target: All drugs targeting Sigma non-opioid intracellular receptor 1
Manufacturer: — full pipeline
Therapeutic area: All drugs in Respiratory
Indication: Drugs for Allergic rhinitis
Indication: Drugs for Common cold
Indication: Drugs for Cough

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing