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oral resveratrol
oral resveratrol is a polyphenol Small molecule drug developed by Assistance Publique - Hôpitaux de Paris. It is currently in Phase 3 development for Cardiovascular disease prevention.
Resveratrol acts as an activator of SIRT1, a protein that plays a role in cellular regulation and metabolism.
Resveratrol acts as an activator of SIRT1, a protein that plays a role in cellular regulation and metabolism. Used for Cardiovascular disease prevention.
At a glance
| Generic name | oral resveratrol |
|---|---|
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Drug class | polyphenol |
| Target | SIRT1 |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
Resveratrol's activation of SIRT1 has been shown to have anti-inflammatory and anti-aging effects. This is thought to occur through the regulation of various cellular pathways, including those involved in metabolism and stress resistance.
Approved indications
- Cardiovascular disease prevention
Common side effects
- Gastrointestinal upset
Key clinical trials
- A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes (NA)
- Resveratrol in Knee Osteoarthritis (PHASE3)
- Clinical and Laboratory Evaluation of Resveratrol Loaded Nanoparticles in the Treatment of Periodontitis: A Randomized Controlled Clinical Trial (PHASE1)
- Evaluation of the Anti-Plaque Effect of a Resveratrol-Based Mouthwash Using a 24-Hour Plaque Re-Growth (PHASE3)
- Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 (PHASE2)
- Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus (PHASE2)
- Strength Training and Resveratrol (NA)
- Resveratrol Stimulates Insulin Sensitivity in Subjects With Obesity and Insulin Resistance (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- oral resveratrol CI brief — competitive landscape report
- oral resveratrol updates RSS · CI watch RSS
- Assistance Publique - Hôpitaux de Paris portfolio CI
Frequently asked questions about oral resveratrol
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Related
- Drug class: All polyphenol drugs
- Target: All drugs targeting SIRT1
- Manufacturer: Assistance Publique - Hôpitaux de Paris — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Cardiovascular disease prevention
- Compare: oral resveratrol vs similar drugs
- Pricing: oral resveratrol cost, discount & access