SIRT1 — Drug Target

All drugs that target SIRT1 — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

polyphenol · SIRT1 activator

Phase 3 pipeline (1)

• oral resveratrol · Assistance Publique - Hôpitaux de Paris · polyphenol · Cardiovascular
  Resveratrol acts as an activator of SIRT1, a protein that plays a role in cellular regulation and metabolism.

Phase 2 pipeline (1)

• ADIPOPLUS · Anterogen Co., Ltd. · SIRT1 activator · Diabetes
  ADIPOPLUS is a small molecule that targets the SIRT1 pathway to enhance adipocyte function and glucose metabolism.