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Miacalcin Calcitonin Salmon Nasal Spray
Miacalcin Calcitonin Salmon Nasal Spray is a Calcitonin receptor agonist Small molecule drug developed by University of Missouri-Columbia. It is currently FDA-approved for Osteoporosis in postmenopausal women, Paget's disease of bone, Hypercalcemia of malignancy. Also known as: Miacalcin, Calcitonin.
Calcitonin salmon is a peptide hormone that binds to calcitonin receptors on osteoclasts to inhibit bone resorption and increase urinary calcium excretion.
Calcitonin salmon is a peptide hormone that binds to calcitonin receptors on osteoclasts to inhibit bone resorption and increase urinary calcium excretion. Used for Osteoporosis in postmenopausal women, Paget's disease of bone, Hypercalcemia of malignancy.
At a glance
| Generic name | Miacalcin Calcitonin Salmon Nasal Spray |
|---|---|
| Also known as | Miacalcin, Calcitonin |
| Sponsor | University of Missouri-Columbia |
| Drug class | Calcitonin receptor agonist |
| Target | Calcitonin receptor |
| Modality | Small molecule |
| Therapeutic area | Endocrinology / Bone Metabolism |
| Phase | FDA-approved |
Mechanism of action
Calcitonin salmon mimics the natural human calcitonin hormone and acts as an osteoclast inhibitor, reducing bone turnover and resorption. It also promotes renal calcium excretion and has analgesic properties in bone pain conditions. The nasal spray formulation allows systemic absorption for treatment of osteoporosis and hypercalcemia.
Approved indications
- Osteoporosis in postmenopausal women
- Paget's disease of bone
- Hypercalcemia of malignancy
Common side effects
- Nasal irritation or rhinitis
- Nausea
- Flushing
- Headache
- Nasal congestion
Key clinical trials
- The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries (PHASE4)
- Hypothyroidism Treated With Calcitonin (PHASE4)
- Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus (NA)
- Calcitonin for Treating X-linked Hypophosphatemia (NA)
- Calcitonin in the Treatment of Fibromyalgia (PHASE4)
- Efficacy of Nasal Spray Calcitonin on Recurrence of Aggressive Central Giant Cell Granuloma (PHASE2)
- A Study of Oral Calcitonin Given at Night to Healthy Postmenopausal Women (PHASE2)
- A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Miacalcin Calcitonin Salmon Nasal Spray CI brief — competitive landscape report
- Miacalcin Calcitonin Salmon Nasal Spray updates RSS · CI watch RSS
- University of Missouri-Columbia portfolio CI
Frequently asked questions about Miacalcin Calcitonin Salmon Nasal Spray
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Related
- Drug class: All Calcitonin receptor agonist drugs
- Target: All drugs targeting Calcitonin receptor
- Manufacturer: University of Missouri-Columbia — full pipeline
- Therapeutic area: All drugs in Endocrinology / Bone Metabolism
- Indication: Drugs for Osteoporosis in postmenopausal women
- Indication: Drugs for Paget's disease of bone
- Indication: Drugs for Hypercalcemia of malignancy
- Also known as: Miacalcin, Calcitonin
- Compare: Miacalcin Calcitonin Salmon Nasal Spray vs similar drugs
- Pricing: Miacalcin Calcitonin Salmon Nasal Spray cost, discount & access