Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus

NCT00478335 NA COMPLETED Results posted

The purpose of this research study is to determine if two investigational medications will be more effective in decreasing urine output than the currently available and routinely used medications in patients with congenital nephrogenic diabetes insipidus (NDI).

Details

Lead sponsor	University of Colorado, Denver
Phase	NA
Status	COMPLETED
Enrolment	4
Start date	2007-05
Completion	2012-10

Conditions

• Nephrogenic Diabetes Insipidus

Interventions

• sildenafil
• calcitonin
• hydrochlorothiazide/amiloride
• indomethacin
• Placebo for sildenafil
• placebo for calcitonin

Primary outcomes

• 24h Urine Volume — 4-days
  urine volume in mL/d

Countries

United States, Denmark