Last reviewed · How we verify

metronidazole and doxycycline

Hospital de Clinicas de Porto Alegre · FDA-approved active Small molecule

metronidazole and doxycycline is a Antibiotic combination Small molecule drug developed by Hospital de Clinicas de Porto Alegre. It is currently FDA-approved for Mixed aerobic-anaerobic bacterial infections, Intra-abdominal infections, Pelvic inflammatory disease.

Metronidazole and doxycycline together provide broad-spectrum antimicrobial coverage by disrupting bacterial DNA synthesis and protein production.

Metronidazole and doxycycline together provide broad-spectrum antimicrobial coverage by disrupting bacterial DNA synthesis and protein production. Used for Mixed aerobic-anaerobic bacterial infections, Intra-abdominal infections, Pelvic inflammatory disease.

At a glance

Generic namemetronidazole and doxycycline
SponsorHospital de Clinicas de Porto Alegre
Drug classAntibiotic combination
TargetBacterial DNA (metronidazole); bacterial 30S ribosome (doxycycline)
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhaseFDA-approved

Mechanism of action

Metronidazole is a nitroimidazole that generates reactive oxygen species to damage bacterial DNA, particularly effective against anaerobes. Doxycycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. Together, they provide synergistic coverage against mixed aerobic and anaerobic infections.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about metronidazole and doxycycline

What is metronidazole and doxycycline?

metronidazole and doxycycline is a Antibiotic combination drug developed by Hospital de Clinicas de Porto Alegre, indicated for Mixed aerobic-anaerobic bacterial infections, Intra-abdominal infections, Pelvic inflammatory disease.

How does metronidazole and doxycycline work?

Metronidazole and doxycycline together provide broad-spectrum antimicrobial coverage by disrupting bacterial DNA synthesis and protein production.

What is metronidazole and doxycycline used for?

metronidazole and doxycycline is indicated for Mixed aerobic-anaerobic bacterial infections, Intra-abdominal infections, Pelvic inflammatory disease, Periodontal infections.

Who makes metronidazole and doxycycline?

metronidazole and doxycycline is developed and marketed by Hospital de Clinicas de Porto Alegre (see full Hospital de Clinicas de Porto Alegre pipeline at /company/hospital-de-clinicas-de-porto-alegre).

What drug class is metronidazole and doxycycline in?

metronidazole and doxycycline belongs to the Antibiotic combination class. See all Antibiotic combination drugs at /class/antibiotic-combination.

What development phase is metronidazole and doxycycline in?

metronidazole and doxycycline is FDA-approved (marketed).

What are the side effects of metronidazole and doxycycline?

Common side effects of metronidazole and doxycycline include Nausea, Diarrhea, Metallic taste (metronidazole), Photosensitivity (doxycycline), Esophageal irritation, Vaginal candidiasis.

What does metronidazole and doxycycline target?

metronidazole and doxycycline targets Bacterial DNA (metronidazole); bacterial 30S ribosome (doxycycline) and is a Antibiotic combination.

Related