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Local infiltration of lidocaine

Kasr El Aini Hospital · Phase 3 active Small molecule

Local infiltration of lidocaine is a Local anesthetic Small molecule drug developed by Kasr El Aini Hospital. It is currently in Phase 3 development for Local anesthesia for surgical and procedural pain control, Infiltration anesthesia for minor surgical procedures.

Lidocaine blocks sodium channels in nerve cell membranes, preventing depolarization and transmission of pain signals.

Lidocaine blocks sodium channels in nerve cell membranes, preventing depolarization and transmission of pain signals. Used for Local anesthesia for surgical and procedural pain control, Infiltration anesthesia for minor surgical procedures.

At a glance

Generic nameLocal infiltration of lidocaine
SponsorKasr El Aini Hospital
Drug classLocal anesthetic
TargetVoltage-gated sodium channels
ModalitySmall molecule
Therapeutic areaAnesthesia / Pain Management
PhasePhase 3

Mechanism of action

Lidocaine is a local anesthetic that works by inhibiting voltage-gated sodium channels in sensory nerve fibers. When infiltrated locally into tissue, it prevents the generation and propagation of action potentials in nociceptive (pain) neurons, thereby producing localized anesthesia. This allows surgical or procedural interventions to be performed without pain sensation in the infiltrated area.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Local infiltration of lidocaine

What is Local infiltration of lidocaine?

Local infiltration of lidocaine is a Local anesthetic drug developed by Kasr El Aini Hospital, indicated for Local anesthesia for surgical and procedural pain control, Infiltration anesthesia for minor surgical procedures.

How does Local infiltration of lidocaine work?

Lidocaine blocks sodium channels in nerve cell membranes, preventing depolarization and transmission of pain signals.

What is Local infiltration of lidocaine used for?

Local infiltration of lidocaine is indicated for Local anesthesia for surgical and procedural pain control, Infiltration anesthesia for minor surgical procedures.

Who makes Local infiltration of lidocaine?

Local infiltration of lidocaine is developed by Kasr El Aini Hospital (see full Kasr El Aini Hospital pipeline at /company/kasr-el-aini-hospital).

What drug class is Local infiltration of lidocaine in?

Local infiltration of lidocaine belongs to the Local anesthetic class. See all Local anesthetic drugs at /class/local-anesthetic.

What development phase is Local infiltration of lidocaine in?

Local infiltration of lidocaine is in Phase 3.

What are the side effects of Local infiltration of lidocaine?

Common side effects of Local infiltration of lidocaine include Systemic toxicity (CNS effects: tremor, seizures), Cardiovascular effects (hypotension, arrhythmias), Allergic reactions, Local tissue irritation or necrosis.

What does Local infiltration of lidocaine target?

Local infiltration of lidocaine targets Voltage-gated sodium channels and is a Local anesthetic.

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