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Xyzal (LEVOCETIRIZINE)

Sanofi · FDA-approved approved Small molecule ✓ Verified May 2026 Quality 50/100

Xyzal (generic name: LEVOCETIRIZINE) is a Histamine-1 Receptor Antagonist Small molecule drug developed by Sanofi. It is currently FDA-approved (first approved 2007) for Allergic rhinitis, Chronic idiopathic urticaria, Seasonal allergic rhinitis.

Xyzal, also known as levocetirizine, is a small molecule medication used to treat conditions such as seasonal and perennial allergic rhinitis, as well as atopic dermatitis. It is available in oral tablet form and is typically taken once daily.

At a glance

Generic nameLEVOCETIRIZINE
SponsorSanofi
Drug classHistamine-1 Receptor Antagonist
TargetHistamine H1 receptor
ModalitySmall molecule
Therapeutic areaImmunology
PhaseFDA-approved
First approval2007

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
FDA labelMechanism, indications, dosing, boxed warnings, drug interactions
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Xyzal

What is Xyzal?

Xyzal (LEVOCETIRIZINE) is a Histamine-1 Receptor Antagonist drug developed by Sanofi, indicated for Allergic rhinitis, Chronic idiopathic urticaria, Seasonal allergic rhinitis.

What is Xyzal used for?

Xyzal is indicated for Allergic rhinitis, Chronic idiopathic urticaria, Seasonal allergic rhinitis.

Who makes Xyzal?

Xyzal is developed and marketed by Sanofi (see full Sanofi pipeline at /company/sanofi).

What is the generic name of Xyzal?

LEVOCETIRIZINE is the generic (nonproprietary) name of Xyzal.

What drug class is Xyzal in?

Xyzal belongs to the Histamine-1 Receptor Antagonist class. See all Histamine-1 Receptor Antagonist drugs at /class/histamine-1-receptor-antagonist.

When was Xyzal approved?

Xyzal was first approved on 2007.

What development phase is Xyzal in?

Xyzal is FDA-approved (marketed).

What are the side effects of Xyzal?

Common side effects of Xyzal include Somnolence, Nasopharyngitis, Fatigue, Dry mouth, Pharyngitis, Pyrexia.

What does Xyzal target?

Xyzal targets Histamine H1 receptor and is a Histamine-1 Receptor Antagonist.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing