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Intravesical antibiotic instillation

Atlantic Health System · FDA-approved active Small molecule

Intravesical antibiotic instillation delivers antibiotics directly into the bladder to prevent or treat urinary tract infections, particularly recurrent infections and those associated with urological procedures.

Intravesical antibiotic instillation delivers antibiotics directly into the bladder to prevent or treat urinary tract infections, particularly recurrent infections and those associated with urological procedures. Used for Recurrent urinary tract infections, Prophylaxis for urological procedures, Neurogenic bladder management.

At a glance

Generic nameIntravesical antibiotic instillation
SponsorAtlantic Health System
Drug classAntibiotic instillation therapy
ModalitySmall molecule
Therapeutic areaUrology / Infectious Disease
PhaseFDA-approved

Mechanism of action

This treatment involves instilling antibiotic solutions directly into the bladder via catheter, allowing high local concentrations of antimicrobial agents to contact the bladder urothelium and eliminate or suppress pathogenic bacteria. The direct bladder delivery minimizes systemic absorption and side effects while providing sustained local antimicrobial activity. This approach is commonly used for prophylaxis in patients with recurrent UTIs, neurogenic bladder, or following urological interventions.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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