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Intracervical lidocaine
Intracervical lidocaine is a Local anesthetic Small molecule drug developed by Bayero University Kano, Nigeria. It is currently FDA-approved for Cervical anesthesia during gynecological procedures, Pain relief during cervical examination or instrumentation. Also known as: lignocaine, Lidocaine injection, paracervical blocker.
Intracervical lidocaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission in cervical tissue.
Intracervical lidocaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission in cervical tissue. Used for Cervical anesthesia during gynecological procedures, Pain relief during cervical examination or instrumentation.
At a glance
| Generic name | Intracervical lidocaine |
|---|---|
| Also known as | lignocaine, Lidocaine injection, paracervical blocker |
| Sponsor | Bayero University Kano, Nigeria |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Gynecology / Pain management |
| Phase | FDA-approved |
Mechanism of action
Lidocaine works by inhibiting the influx of sodium ions through voltage-gated sodium channels in nerve fibers, thereby preventing depolarization and the generation of action potentials. When applied intracervically, it produces localized anesthesia of the cervix and surrounding tissues, reducing pain sensation during gynecological procedures or examinations.
Approved indications
- Cervical anesthesia during gynecological procedures
- Pain relief during cervical examination or instrumentation
Common side effects
- Local irritation or burning at application site
- Allergic reaction (rare with amide lidocaine)
- Systemic toxicity (if absorbed in high amounts)
Key clinical trials
- Intracervical Block During Laminaria Insertion (NA)
- Managing Outpatient Hysteroscopy-associated Pain (NA)
- Paracervical Versus Intracervical Lidocaine (NA)
- Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion (PHASE4)
- The Value of Endocervical and Endometrial Lidocaine Flushing Before Office Hystroscopy (PHASE4)
- Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief in HSG in a Tertiary Hospital in Kano (PHASE4)
- Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence? (NA)
- Intracervical Lidocaine Gel for IUD Insertional Pain (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Intracervical lidocaine CI brief — competitive landscape report
- Intracervical lidocaine updates RSS · CI watch RSS
- Bayero University Kano, Nigeria portfolio CI
Frequently asked questions about Intracervical lidocaine
What is Intracervical lidocaine?
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Is Intracervical lidocaine also known as anything else?
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Related
- Drug class: All Local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Bayero University Kano, Nigeria — full pipeline
- Therapeutic area: All drugs in Gynecology / Pain management
- Indication: Drugs for Cervical anesthesia during gynecological procedures
- Indication: Drugs for Pain relief during cervical examination or instrumentation
- Also known as: lignocaine, Lidocaine injection, paracervical blocker
- Compare: Intracervical lidocaine vs similar drugs
- Pricing: Intracervical lidocaine cost, discount & access