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intraarticular injection with ropivacaine
intraarticular injection with ropivacaine is a Local anesthetic Small molecule drug developed by Hvidovre University Hospital. It is currently FDA-approved for Intra-articular anesthesia and analgesia for joint procedures and post-operative pain management.
Ropivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce localized anesthesia and analgesia.
Ropivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce localized anesthesia and analgesia. Used for Intra-articular anesthesia and analgesia for joint procedures and post-operative pain management.
At a glance
| Generic name | intraarticular injection with ropivacaine |
|---|---|
| Sponsor | Hvidovre University Hospital |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
Ropivacaine is an amide-type local anesthetic that reversibly inhibits sodium influx through voltage-gated sodium channels in nerve cell membranes. When administered intra-articularly, it diffuses into nearby nerve tissues and synovial structures, producing regional anesthesia and pain relief in the joint. This mechanism allows for perioperative pain control and post-operative analgesia without systemic effects.
Approved indications
- Intra-articular anesthesia and analgesia for joint procedures and post-operative pain management
Common side effects
- Local tissue irritation
- Transient joint swelling
- Systemic toxicity (if absorbed in high concentrations)
- Allergic reaction
Key clinical trials
- OMT for Adhesive Capsulitis (PHASE4)
- Suprascapular Nerve Block to Improve Tolerance and Outcomes of Shoulder Hydrodistension in Adhesive Capsulitis (NA)
- Connective Tissue Matrix Compared to Steroid Injections for Rotator Cuff Tendinopathy (NA)
- Trial for Treating Painful Degenerative Disc Disease (NA)
- Frozen Shoulder Treatment with Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block (NA)
- "Comparison of Intra-articular of 0.2% Ropivacaine vs. 0.75% Ropivacaine in Postoperative of Knee Arthroscopy" (PHASE4)
- Triamcinolone Ketorolac (TriKe) Knee Trial (PHASE4)
- Temporomandibular Joint Arthrocentesis With Infiltration of PRP + Ropivacaine Versus PRP (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
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- intraarticular injection with ropivacaine CI brief — competitive landscape report
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Frequently asked questions about intraarticular injection with ropivacaine
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Related
- Drug class: All Local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Hvidovre University Hospital — full pipeline
- Therapeutic area: All drugs in Anesthesia/Pain Management
- Indication: Drugs for Intra-articular anesthesia and analgesia for joint procedures and post-operative pain management
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