Last reviewed · How we verify
GSK2585823(CLDM 1%-BPO 3% gel)
GSK2585823(CLDM 1%-BPO 3% gel) is a Topical antibiotic combination Small molecule drug developed by GlaxoSmithKline. It is currently in Phase 3 development for Acne vulgaris. Also known as: GSK2585823.
This combination gel delivers clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial and keratolytic agent) topically to reduce acne-causing bacteria and inflammation.
This combination gel delivers clindamycin (an antibiotic) and benzoyl peroxide (an antimicrobial and keratolytic agent) topically to reduce acne-causing bacteria and inflammation. Used for Acne vulgaris.
At a glance
| Generic name | GSK2585823(CLDM 1%-BPO 3% gel) |
|---|---|
| Also known as | GSK2585823 |
| Sponsor | GlaxoSmithKline |
| Drug class | Topical antibiotic combination |
| Target | Bacterial protein synthesis (clindamycin); oxidative antimicrobial activity (benzoyl peroxide) |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
Clindamycin is a lincosamide antibiotic that inhibits bacterial protein synthesis, effective against Cutibacterium acnes. Benzoyl peroxide acts as an oxidizing agent that kills bacteria and helps shed dead skin cells. The combination targets both bacterial and inflammatory components of acne pathogenesis.
Approved indications
- Acne vulgaris
Common side effects
- Skin irritation
- Erythema
- Dryness
- Peeling
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- GSK2585823(CLDM 1%-BPO 3% gel) CI brief — competitive landscape report
- GSK2585823(CLDM 1%-BPO 3% gel) updates RSS · CI watch RSS
- GlaxoSmithKline portfolio CI
Frequently asked questions about GSK2585823(CLDM 1%-BPO 3% gel)
What is GSK2585823(CLDM 1%-BPO 3% gel)?
How does GSK2585823(CLDM 1%-BPO 3% gel) work?
What is GSK2585823(CLDM 1%-BPO 3% gel) used for?
Who makes GSK2585823(CLDM 1%-BPO 3% gel)?
Is GSK2585823(CLDM 1%-BPO 3% gel) also known as anything else?
What drug class is GSK2585823(CLDM 1%-BPO 3% gel) in?
What development phase is GSK2585823(CLDM 1%-BPO 3% gel) in?
What are the side effects of GSK2585823(CLDM 1%-BPO 3% gel)?
What does GSK2585823(CLDM 1%-BPO 3% gel) target?
Related
- Drug class: All Topical antibiotic combination drugs
- Target: All drugs targeting Bacterial protein synthesis (clindamycin); oxidative antimicrobial activity (benzoyl peroxide)
- Manufacturer: GlaxoSmithKline — full pipeline
- Therapeutic area: All drugs in Dermatology
- Indication: Drugs for Acne vulgaris
- Also known as: GSK2585823
- Compare: GSK2585823(CLDM 1%-BPO 3% gel) vs similar drugs
- Pricing: GSK2585823(CLDM 1%-BPO 3% gel) cost, discount & access