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General anesthetic
General anesthetic is a General anesthetic Small molecule drug developed by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine. It is currently FDA-approved for Induction and maintenance of general anesthesia for surgical procedures. Also known as: total intravenous anesthesia, Fentanyl based general anaesthesia, NOL-directed general anesthesia, control group.
General anesthetics depress the central nervous system to produce unconsciousness, analgesia, and muscle relaxation for surgical procedures.
General anesthetics depress the central nervous system to produce unconsciousness, analgesia, and muscle relaxation for surgical procedures. Used for Induction and maintenance of general anesthesia for surgical procedures.
At a glance
| Generic name | General anesthetic |
|---|---|
| Also known as | total intravenous anesthesia, Fentanyl based general anaesthesia, NOL-directed general anesthesia, control group, general anesthesia |
| Sponsor | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine |
| Drug class | General anesthetic |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | FDA-approved |
Mechanism of action
General anesthetics work through multiple mechanisms including enhancement of inhibitory GABAergic neurotransmission and/or suppression of excitatory glutamatergic signaling in the brain. This results in loss of consciousness, suppression of reflexes, and analgesia. The specific molecular targets vary depending on the anesthetic agent used (e.g., propofol acts on GABA-A receptors, while nitrous oxide and ketamine have different primary targets).
Approved indications
- Induction and maintenance of general anesthesia for surgical procedures
Common side effects
- Respiratory depression
- Hypotension
- Bradycardia
- Postoperative nausea and vomiting
- Emergence delirium
Key clinical trials
- Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients" (NA)
- Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?
- The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
- Educational Cartoon to Reduce Preoperative Anxiety in Children (CALM-KIDS) (NA)
- Effect of Bladder Distension on Dosimetry in Brachytherapy of Cervical Cancer (NA)
- Acupuncture for Blood Pressure Fluctuation During Total Laparoscopic Hysterectomy (NA)
- Magnetic Compression Anastomosis Procedure for Partial Jejunoileal Anastomosis: Assessing the Viability of an Innovative Metabolic Approach (NA)
- Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- General anesthetic CI brief — competitive landscape report
- General anesthetic updates RSS · CI watch RSS
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine portfolio CI
Frequently asked questions about General anesthetic
What is General anesthetic?
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Related
- Drug class: All General anesthetic drugs
- Manufacturer: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine — full pipeline
- Therapeutic area: All drugs in Anesthesiology
- Indication: Drugs for Induction and maintenance of general anesthesia for surgical procedures
- Also known as: total intravenous anesthesia, Fentanyl based general anaesthesia, NOL-directed general anesthesia, control group, general anesthesia
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing