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Fentanyl Opioid anesthesia
Fentanyl Opioid anesthesia is a Opioid agonist Small molecule drug developed by University of Alexandria. It is currently FDA-approved for General anesthesia induction and maintenance, Analgesia during and after surgery, Sedation in intensive care settings.
Fentanyl binds to opioid receptors in the central nervous system to produce anesthesia, analgesia, and sedation.
Fentanyl binds to opioid receptors in the central nervous system to produce anesthesia, analgesia, and sedation. Used for General anesthesia induction and maintenance, Analgesia during and after surgery, Sedation in intensive care settings.
At a glance
| Generic name | Fentanyl Opioid anesthesia |
|---|---|
| Sponsor | University of Alexandria |
| Drug class | Opioid agonist |
| Target | Mu (μ) opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Fentanyl is a synthetic opioid agonist that acts primarily on mu (μ) opioid receptors in the brain and spinal cord. This binding suppresses pain signal transmission and produces profound analgesia and sedation. In anesthetic practice, it is used to induce and maintain general anesthesia, often in combination with other agents.
Approved indications
- General anesthesia induction and maintenance
- Analgesia during and after surgery
- Sedation in intensive care settings
Common side effects
- Respiratory depression
- Hypotension
- Bradycardia
- Chest wall rigidity
- Nausea and vomiting
- Delayed recovery
Key clinical trials
- The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
- EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives (NA)
- Cardiac Index and General Anesthesia Without Opioid. (PHASE2, PHASE3)
- Lidocaine-based Versus Opioid-based Induction of Anesthesia in Emergency Laparotomy (PHASE4)
- qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery (NA)
- Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery (PHASE2)
- Evaluation of Response to Pain From Skull Pin Fixation in Craniotomies
- Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Fentanyl Opioid anesthesia CI brief — competitive landscape report
- Fentanyl Opioid anesthesia updates RSS · CI watch RSS
- University of Alexandria portfolio CI
Frequently asked questions about Fentanyl Opioid anesthesia
What is Fentanyl Opioid anesthesia?
How does Fentanyl Opioid anesthesia work?
What is Fentanyl Opioid anesthesia used for?
Who makes Fentanyl Opioid anesthesia?
What drug class is Fentanyl Opioid anesthesia in?
What development phase is Fentanyl Opioid anesthesia in?
What are the side effects of Fentanyl Opioid anesthesia?
What does Fentanyl Opioid anesthesia target?
Related
- Drug class: All Opioid agonist drugs
- Target: All drugs targeting Mu (μ) opioid receptor
- Manufacturer: University of Alexandria — full pipeline
- Therapeutic area: All drugs in Anesthesia
- Indication: Drugs for General anesthesia induction and maintenance
- Indication: Drugs for Analgesia during and after surgery
- Indication: Drugs for Sedation in intensive care settings
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing