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Dulox capsule (60mg)
Dulox capsule (60mg) is a Serotonin-norepinephrine reuptake inhibitor (SNRI) Small molecule drug developed by Ain Shams University. It is currently FDA-approved for Major depressive disorder, Generalized anxiety disorder, Diabetic peripheral neuropathic pain. Also known as: Dulox was presented as CYMBALTA® capsules manufactured by Lilly del Caribe Inc..
Duloxetine inhibits the reuptake of serotonin and norepinephrine in the central nervous system, increasing their availability at synaptic sites.
Dulox capsule (60mg) is a small molecule neurokinin 1 receptor antagonist used to treat postoperative pain control. It belongs to the antagonist drug class and targets the substance-P receptor.
At a glance
| Generic name | Dulox capsule (60mg) |
|---|---|
| Also known as | Dulox was presented as CYMBALTA® capsules manufactured by Lilly del Caribe Inc. |
| Sponsor | Ain Shams University |
| Drug class | Serotonin-norepinephrine reuptake inhibitor (SNRI) |
| Target | Serotonin transporter (SERT) and norepinephrine transporter (NET) |
| Modality | Small molecule |
| Therapeutic area | Psychiatry / Neurology |
| Phase | FDA-approved |
Mechanism of action
Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that blocks the reuptake transporters for both serotonin and norepinephrine, leading to increased neurotransmitter concentrations in the synaptic cleft. This dual mechanism enhances monoaminergic neurotransmission and is thought to improve mood regulation and pain perception. The drug is used primarily for depression, anxiety disorders, and chronic pain conditions.
Approved indications
- Major depressive disorder
- Generalized anxiety disorder
- Diabetic peripheral neuropathic pain
- Fibromyalgia
- Chronic musculoskeletal pain
Common side effects
- Nausea
- Dizziness
- Somnolence
- Dry mouth
- Fatigue
- Constipation
- Decreased appetite
- Sexual dysfunction
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Dulox capsule (60mg) CI brief — competitive landscape report
- Dulox capsule (60mg) updates RSS · CI watch RSS
- Ain Shams University portfolio CI
Frequently asked questions about Dulox capsule (60mg)
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Related
- Drug class: All Serotonin-norepinephrine reuptake inhibitor (SNRI) drugs
- Target: All drugs targeting Serotonin transporter (SERT) and norepinephrine transporter (NET)
- Manufacturer: Ain Shams University — full pipeline
- Therapeutic area: All drugs in Psychiatry / Neurology
- Indication: Drugs for Major depressive disorder
- Indication: Drugs for Generalized anxiety disorder
- Indication: Drugs for Diabetic peripheral neuropathic pain
- Also known as: Dulox was presented as CYMBALTA® capsules manufactured by Lilly del Caribe Inc.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing