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Bentyl (dicycloverine)
Bentyl (generic name: dicycloverine) is a Anticholinergic drug developed by Forest Labs Inc. It is currently FDA-approved (first approved 1950) for Irritable bowel syndrome.
Bentyl (dicycloverine) is a small molecule anticholinergic medication originally developed by Forest Labs Inc and currently owned by the same company. It targets the muscarinic acetylcholine receptor M4 and is FDA approved for the treatment of irritable bowel syndrome. Bentyl works by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions in the gastrointestinal tract. As an off-patent medication, Bentyl is likely available in generic forms. Key safety considerations include potential anticholinergic side effects such as dry mouth and constipation.
At a glance
| Generic name | dicycloverine |
|---|---|
| Sponsor | Forest Labs Inc |
| Drug class | Anticholinergic |
| Target | Histamine H2 receptor |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
| First approval | 1950 |
Approved indications
- Irritable bowel syndrome
Common side effects
Key clinical trials
- Effects of Pre-procedure and Intra-procedure Simethicone and Dicyclomine Administration in Improving Quality of Endoscopic Reterograde Cholangipancreaticography (ERCP) (PHASE4)
- Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin Under Fed Conditions in Healthy Volunteers (PHASE1)
- Therapeutic Implications of Acutaping on Nausea and Vomiting During Pregnancy (NA)
- Pharmacokinetics and Bioequivalence of Doxylamine + Pyridoxine, Film-coated, Enteric-soluble Tablets, and Diclectin, Delayed Release Tablets, in Healthy Volunteers (NA)
- Effectiveness of Acupuncture and Doxylamine/Pyridoxine for Moderate to Severe Nausea and Vomiting in Pregnancy (PHASE3)
- The Efficacy Of Diclectin® For Nausea And Vomiting Of Pregnancy (PHASE3)
- A Multicenter Trial of the Efficacy and Safety of Diclegis® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents (PHASE4)
- A Study to Investigate Differences in the Extent and Rate of Absorption of Doxylamine/Pyridoxine From 2 Different Products Under Fasting Conditions (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Bentyl CI brief — competitive landscape report
- Bentyl updates RSS · CI watch RSS
- Forest Labs Inc portfolio CI
Frequently asked questions about Bentyl
What is Bentyl?
What is Bentyl used for?
Who makes Bentyl?
What is the generic name of Bentyl?
What drug class is Bentyl in?
When was Bentyl approved?
What development phase is Bentyl in?
What does Bentyl target?
Related
- Drug class: All Anticholinergic drugs
- Target: All drugs targeting Histamine H2 receptor
- Manufacturer: Forest Labs Inc — full pipeline
- Therapeutic area: All drugs in Neuroscience
- Indication: Drugs for Irritable bowel syndrome
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing