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borage seed oil

National Center for Complementary and Integrative Health (NCCIH) · Phase 3 active Small molecule

Borage seed oil is used to provide essential fatty acids, particularly gamma-linolenic acid (GLA), which may help reduce inflammation and improve symptoms of conditions such as eczema and rheumatoid arthritis.

Borage seed oil is used to provide essential fatty acids, particularly gamma-linolenic acid (GLA), which may help reduce inflammation and improve symptoms of conditions such as eczema and rheumatoid arthritis. Used for Eczema, Rheumatoid arthritis.

At a glance

Generic nameborage seed oil
Also known asGLA
SponsorNational Center for Complementary and Integrative Health (NCCIH)
ModalitySmall molecule
Therapeutic areaDermatology
PhasePhase 3

Mechanism of action

The exact mechanism of borage seed oil is not fully understood, but it is thought to work by reducing inflammation and improving the body's response to injury. This may be due to the presence of GLA, which is converted into prostaglandins that have anti-inflammatory effects. Additionally, borage seed oil may also have antioxidant properties, which can help protect cells from damage.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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