The Effects of Dietary Supplementation With Omega-3 Fatty Acids on Symptoms of Dry Eye

NCT03141931 NA COMPLETED Results posted

The aim of this study is to compare ocular symptoms and signs when the test nutraceutical formulation (combination of flaxseed oil, borage oil and fish oil omega-3 fatty acids) is consumed daily over a 3 month period, with a control capsule that contains polyethylene glycol (PEG), oleic acid and propylene glycol, which are found in many pharmaceutical products and are generally considered to be biologically inert and safe. There is good evidence that the consumption of oily fish has a protective effect against dry eye, and other studies have provided evidence of the beneficial effect of supplementation with omega-3 essential fatty acids in the treatment of dry eye disease. However, there have been limited well designed clinical trials investigating the potential for nutraceutical dietary supplementation to impact ocular comfort. To date, no controlled, randomised clinical trials have been conducted to evaluate the test nutraceutical formulation. Therefore, the purpose of this study is to conduct a randomized, placebo-controlled, double-masked study to investigate the effects of dietary supplementation with a combination of flaxseed oil, borage oil and fish oil omega-3 fatty acids on ocular comfort including signs and symptoms of dry eye.

Details

Lead sponsor	The University of New South Wales
Phase	NA
Status	COMPLETED
Enrolment	119
Start date	Mon Aug 21 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Oct 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Dry Eye

Interventions

• Supplement
• Placebo

Countries

Australia