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Borage and Echium Seed Oils
Borage and Echium seed oils provide omega-3 and omega-6 polyunsaturated fatty acids that modulate inflammatory pathways and immune responses.
Borage and Echium seed oils provide omega-3 and omega-6 polyunsaturated fatty acids that modulate inflammatory pathways and immune responses. Used for Rheumatoid arthritis.
At a glance
| Generic name | Borage and Echium Seed Oils |
|---|---|
| Sponsor | Brigham and Women's Hospital |
| Drug class | Botanical supplement / Omega-3/Omega-6 polyunsaturated fatty acid |
| Modality | Small molecule |
| Therapeutic area | Immunology / Rheumatology |
| Phase | Phase 3 |
Mechanism of action
These plant-derived oils are rich in gamma-linolenic acid (GLA) and eicosapentaenoic acid (EPA), which are converted to anti-inflammatory mediators that suppress pro-inflammatory cytokine production and reduce immune cell activation. The fatty acids compete with arachidonic acid metabolism, shifting the balance toward resolution of inflammation and potentially benefiting autoimmune and inflammatory conditions.
Approved indications
- Rheumatoid arthritis
Common side effects
- Gastrointestinal upset
- Dyspepsia
- Nausea
- Rash
Key clinical trials
- Borage and Echium Seed Oils for Asthma (PHASE3)
- Treatment of Bronchial Asthma With Borage and Echium Seed Oils (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Borage and Echium Seed Oils CI brief — competitive landscape report
- Borage and Echium Seed Oils updates RSS · CI watch RSS
- Brigham and Women's Hospital portfolio CI