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Bolus without paracetamol
Bolus without paracetamol is a Small molecule drug developed by University of Helsinki. It is currently FDA-approved for Treatment of acute conditions such as severe allergic reactions, anaphylaxis, and acute pain management. Also known as: Paracetamol=acetaminophen.
Bolus injections deliver a concentrated dose of medication directly into the bloodstream, bypassing the digestive system.
Bolus is a type of continuous preperitoneal infusion of local anesthetics, such as ropivacaine, used to manage pain, particularly postoperative pain. It has also been studied for its potential benefits in conditions like obesity and postoperative pain following bariatric surgery and laparoscopic procedures.
At a glance
| Generic name | Bolus without paracetamol |
|---|---|
| Also known as | Paracetamol=acetaminophen |
| Sponsor | University of Helsinki |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
This allows for rapid absorption and increased bioavailability of the medication, which can be particularly beneficial for drugs that are poorly absorbed orally or have a narrow therapeutic index.
Approved indications
- Treatment of acute conditions such as severe allergic reactions, anaphylaxis, and acute pain management
Common side effects
- Injection site reactions
Key clinical trials
- Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) (PHASE1, PHASE2)
- Femoral Rami Obturator Nerve Trunk (FRONT) Block in Intramedullary Nail Surgery . (NA)
- Intrathecal Morphine for Recovery and Outcomes After VATS (NA)
- Erector Spinae Plane Block vs Quadratus Lumborum Block for Laparoscopic Nephrectomy (NA)
- Intravenous Acetaminophen for Postoperative Delirium in Older Patients Recovering From Major Noncardiac Surgery (PHASE2, PHASE3)
- Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study) (PHASE3)
- Evaluation of the Effectiveness of the Administration of Local Anesthetics Via Two Catheters Placed During Surgery, and Study of the Benefits on Respiratory Function and Therefore on Recovery Time (NA)
- Erector Spinae Plane Block Versus Subcostal Anterior Quadratus Lumborum Block in Laparoscopic Cholecystectomy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Bolus without paracetamol CI brief — competitive landscape report
- Bolus without paracetamol updates RSS · CI watch RSS
- University of Helsinki portfolio CI
Frequently asked questions about Bolus without paracetamol
What is Bolus without paracetamol?
How does Bolus without paracetamol work?
What is Bolus without paracetamol used for?
Who makes Bolus without paracetamol?
Is Bolus without paracetamol also known as anything else?
What development phase is Bolus without paracetamol in?
What are the side effects of Bolus without paracetamol?
Related
- Manufacturer: University of Helsinki — full pipeline
- Indication: Drugs for Treatment of acute conditions such as severe allergic reactions, anaphylaxis, and acute pain management
- Also known as: Paracetamol=acetaminophen
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing