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Acetylsalicylic morning
Acetylsalicylic morning is a Nonsteroidal anti-inflammatory drug (NSAID); antiplatelet agent Small molecule drug developed by Basque Health Service. It is currently in Phase 3 development for Cardiovascular disease prevention (secondary prevention post-myocardial infarction or stroke), Acute coronary syndrome, Pain and fever management. Also known as: Asa, Low dose, aspirine.
Acetylsalicylic acid irreversibly inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins and thromboxane to provide anti-inflammatory, analgesic, and antiplatelet effects.
Acetylsalicylic acid irreversibly inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins and thromboxane to provide anti-inflammatory, analgesic, and antiplatelet effects. Used for Cardiovascular disease prevention (secondary prevention post-myocardial infarction or stroke), Acute coronary syndrome, Pain and fever management.
At a glance
| Generic name | Acetylsalicylic morning |
|---|---|
| Also known as | Asa, Low dose, aspirine |
| Sponsor | Basque Health Service |
| Drug class | Nonsteroidal anti-inflammatory drug (NSAID); antiplatelet agent |
| Target | Cyclooxygenase-1 (COX-1); Cyclooxygenase-2 (COX-2) |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular; Pain management; Inflammation |
| Phase | Phase 3 |
Mechanism of action
Acetylsalicylic acid (aspirin) acetylates serine residues on COX-1 and COX-2 enzymes, permanently blocking their catalytic activity. This reduces synthesis of prostaglandins (involved in inflammation and pain) and thromboxane A2 (a platelet aggregator), resulting in anti-inflammatory, pain-relieving, and blood-thinning effects. The antiplatelet effect is particularly durable because it affects long-lived platelets that cannot synthesize new COX-1.
Approved indications
- Cardiovascular disease prevention (secondary prevention post-myocardial infarction or stroke)
- Acute coronary syndrome
- Pain and fever management
- Inflammatory conditions
Common side effects
- Gastrointestinal bleeding or ulceration
- Dyspepsia
- Nausea
- Increased bleeding risk
- Hypersensitivity reactions
Key clinical trials
- Helping Osteoarthritis Patients to Walk With NSAID (PHASE4)
- LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention (PHASE4)
- Aspirin in Young Psychotic Patients (PHASE2, PHASE3)
- TIME ASPIRIN: Chronotherapy With Aspirin for Reduction of Cardiovascular Disease (NA)
- Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease (PHASE4)
- N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder (PHASE2)
- Antiplatlet Effects of Standardized Tomato Extract in Hypertensive Subjects (PHASE4)
- Loss of Effect of Aspirin on Platelet Aggregation During Chronic Administration (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Acetylsalicylic morning CI brief — competitive landscape report
- Acetylsalicylic morning updates RSS · CI watch RSS
- Basque Health Service portfolio CI
Frequently asked questions about Acetylsalicylic morning
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Related
- Drug class: All Nonsteroidal anti-inflammatory drug (NSAID); antiplatelet agent drugs
- Target: All drugs targeting Cyclooxygenase-1 (COX-1); Cyclooxygenase-2 (COX-2)
- Manufacturer: Basque Health Service — full pipeline
- Therapeutic area: All drugs in Cardiovascular; Pain management; Inflammation
- Indication: Drugs for Cardiovascular disease prevention (secondary prevention post-myocardial infarction or stroke)
- Indication: Drugs for Acute coronary syndrome
- Indication: Drugs for Pain and fever management
- Also known as: Asa, Low dose, aspirine
- Compare: Acetylsalicylic morning vs similar drugs
- Pricing: Acetylsalicylic morning cost, discount & access