Last reviewed · How we verify
Tonic-clonic epilepsy
Approved treatments
- Topamax · Janssen
- Phenytoin Sodium · Viatris
Phenytoin Sodium works by stabilizing the threshold against hyperexcitability caused by excessive stimulation. - Tegretol · Novartis AG (originally Geigy)
Carbamazepine reduces polysynaptic responses and blocks post-tetanic potentiation, potentially alleviating seizures and pain. - Metylfenemal
- Metabarbital · AbbVie
- Carbamazepin · Enanta Pharmaceuticals, Inc
- phenobarbitone · Institute of Child Health
- Mysoline · Bausch Health
- Peganone · Recordati
- Dilantin · Pfizer
Phenytoin exerts its therapeutic effect by voltage-dependent blockade of membrane sodium channels. - Topamax · Ataturk University
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Tonic-clonic epilepsy patent landscape — cliff calendar, originator estates, attackable patents
- Tonic-clonic epilepsy treatment landscape brief
- Tonic-clonic epilepsy treatment updates RSS
Frequently asked questions about Tonic-clonic epilepsy
What drugs treat Tonic-clonic epilepsy?
Tracked treatments include Topamax, Phenytoin Sodium, Tegretol, Metylfenemal, Metabarbital, Carbamazepin, phenobarbitone, Mysoline.
What is the treatment for Tonic-clonic epilepsy?
Standard treatment for Tonic-clonic epilepsy includes Topamax, Phenytoin Sodium, Tegretol, Metylfenemal, Metabarbital. See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Tonic-clonic epilepsy patent cliff · Tonic-clonic epilepsy CI report
- Treatment: Topamax · Janssen
- Treatment: Phenytoin Sodium · Viatris
- Treatment: Tegretol · Novartis AG (originally Geigy)
- Treatment: Metylfenemal
- Treatment: Metabarbital · AbbVie
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing